Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1929437..1929582 Replicon chromosome
Accession NZ_CP102841
Organism Klebsiella pneumoniae strain KP4863

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929473..1929575 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1929437..1929582 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV397_RS09175 (NV397_09175) 1924567..1926627 + 2061 WP_004151449.1 oligopeptidase B -
NV397_RS09180 (NV397_09180) 1926631..1927290 - 660 WP_002911407.1 exodeoxyribonuclease X -
NV397_RS09185 (NV397_09185) 1927369..1927599 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NV397_RS09190 (NV397_09190) 1927712..1928086 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NV397_RS09195 (NV397_09195) 1928090..1928959 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NV397_RS09200 (NV397_09200) 1928976..1929314 + 339 WP_016529031.1 YebY family protein -
- 1929437..1929582 - 146 - - Antitoxin
- 1929473..1929575 + 103 - - Toxin
NV397_RS09205 (NV397_09205) 1929950..1930093 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NV397_RS09210 (NV397_09210) 1930198..1931166 - 969 WP_014907334.1 VirK/YbjX family protein -
NV397_RS09215 (NV397_09215) 1931323..1931976 + 654 WP_163621953.1 protein-serine/threonine phosphatase -
NV397_RS09220 (NV397_09220) 1931973..1932164 - 192 WP_002911395.1 YebW family protein -
NV397_RS09225 (NV397_09225) 1932262..1932501 - 240 WP_002911393.1 YebV family protein -
NV397_RS09230 (NV397_09230) 1932617..1934050 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254265 NZ_CP102841:1929473-1929575 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254265 NZ_CP102841:c1929582-1929437 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References