Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1980179..1980324 Replicon chromosome
Accession NZ_CP102836
Organism Klebsiella pneumoniae strain KP0079

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1980215..1980317 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1980179..1980324 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV396_RS09645 (NV396_09645) 1975309..1977369 + 2061 WP_004151449.1 oligopeptidase B -
NV396_RS09650 (NV396_09650) 1977373..1978032 - 660 WP_002911407.1 exodeoxyribonuclease X -
NV396_RS09655 (NV396_09655) 1978111..1978341 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NV396_RS09660 (NV396_09660) 1978454..1978828 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NV396_RS09665 (NV396_09665) 1978832..1979701 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NV396_RS09670 (NV396_09670) 1979718..1980056 + 339 WP_002911404.1 YebY family protein -
- 1980179..1980324 - 146 - - Antitoxin
- 1980215..1980317 + 103 - - Toxin
NV396_RS09675 (NV396_09675) 1980692..1980835 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NV396_RS09680 (NV396_09680) 1980940..1981908 - 969 WP_004151446.1 VirK/YbjX family protein -
NV396_RS09685 (NV396_09685) 1982065..1982718 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NV396_RS09690 (NV396_09690) 1982715..1982906 - 192 WP_002911395.1 YebW family protein -
NV396_RS09695 (NV396_09695) 1983004..1983243 - 240 WP_002911393.1 YebV family protein -
NV396_RS09700 (NV396_09700) 1983359..1984792 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254240 NZ_CP102836:1980215-1980317 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254240 NZ_CP102836:c1980324-1980179 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References