Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1969780..1969925 Replicon chromosome
Accession NZ_CP102833
Organism Klebsiella pneumoniae strain KP4962

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1969816..1969918 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1969780..1969925 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV394_RS09545 1964910..1966970 + 2061 WP_004899137.1 oligopeptidase B -
NV394_RS09550 1966974..1967633 - 660 WP_002911407.1 exodeoxyribonuclease X -
NV394_RS09555 1967712..1967942 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NV394_RS09560 1968055..1968429 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NV394_RS09565 1968433..1969302 + 870 WP_004899136.1 copper homeostasis membrane protein CopD -
NV394_RS09570 1969319..1969657 + 339 WP_002911404.1 YebY family protein -
- 1969780..1969925 - 146 - - Antitoxin
- 1969816..1969918 + 103 - - Toxin
NV394_RS09575 1970293..1970436 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NV394_RS09580 1970541..1971509 - 969 WP_004151446.1 VirK/YbjX family protein -
NV394_RS09585 1971666..1972319 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
NV394_RS09590 1972316..1972507 - 192 WP_002911395.1 YebW family protein -
NV394_RS09595 1972605..1972844 - 240 WP_002911393.1 YebV family protein -
NV394_RS09600 1972960..1974393 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254225 NZ_CP102833:1969816-1969918 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254225 NZ_CP102833:c1969925-1969780 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References