Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3946471..3947131 Replicon chromosome
Accession NZ_CP102827
Organism Salmonella enterica subsp. enterica serovar Indiana strain XZ14C1328

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag NV345_RS19150 Protein ID WP_000244755.1
Coordinates 3946471..3946884 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NV345_RS19155 Protein ID WP_000351186.1
Coordinates 3946865..3947131 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV345_RS19130 (3942412) 3942412..3944145 - 1734 WP_023227724.1 single-stranded-DNA-specific exonuclease RecJ -
NV345_RS19135 (3944151) 3944151..3944864 - 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NV345_RS19140 (3944888) 3944888..3945784 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NV345_RS19145 (3945897) 3945897..3946418 + 522 WP_001055885.1 flavodoxin FldB -
NV345_RS19150 (3946471) 3946471..3946884 - 414 WP_000244755.1 protein YgfX Toxin
NV345_RS19155 (3946865) 3946865..3947131 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NV345_RS19160 (3947381) 3947381..3948361 + 981 WP_017441090.1 tRNA-modifying protein YgfZ -
NV345_RS19165 (3948444) 3948444..3949430 - 987 WP_023226548.1 IS110 family transposase -
NV345_RS19170 (3949688) 3949688..3950347 - 660 WP_000250289.1 hemolysin III family protein -
NV345_RS19175 (3950511) 3950511..3950822 - 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T254214 WP_000244755.1 NZ_CP102827:c3946884-3946471 [Salmonella enterica subsp. enterica serovar Indiana]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT254214 WP_000351186.1 NZ_CP102827:c3947131-3946865 [Salmonella enterica subsp. enterica serovar Indiana]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References