Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 186138..186772 Replicon chromosome
Accession NZ_CP102780
Organism Pandoraea commovens strain LB-19-202-79

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NTU39_RS01190 Protein ID WP_150663849.1
Coordinates 186353..186772 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NTU39_RS01185 Protein ID WP_150663848.1
Coordinates 186138..186338 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTU39_RS01165 (NTU39_01165) 181165..181566 + 402 WP_039394559.1 PaaI family thioesterase -
NTU39_RS01170 (NTU39_01170) 181619..182464 + 846 WP_150663847.1 patatin-like phospholipase family protein -
NTU39_RS01175 (NTU39_01175) 182531..183541 - 1011 WP_257959024.1 D-2-hydroxyacid dehydrogenase family protein -
NTU39_RS01180 (NTU39_01180) 183995..185881 + 1887 WP_257959025.1 phosphoenolpyruvate carboxykinase (GTP) -
NTU39_RS01185 (NTU39_01185) 186138..186338 + 201 WP_150663848.1 DNA-binding protein Antitoxin
NTU39_RS01190 (NTU39_01190) 186353..186772 + 420 WP_150663849.1 type II toxin-antitoxin system VapC family toxin Toxin
NTU39_RS01195 (NTU39_01195) 186796..187428 - 633 WP_039394571.1 response regulator transcription factor -
NTU39_RS01200 (NTU39_01200) 187425..188813 - 1389 WP_150663850.1 cache domain-containing protein -
NTU39_RS01205 (NTU39_01205) 189244..191310 + 2067 WP_150663851.1 carbon starvation CstA family protein -
NTU39_RS01210 (NTU39_01210) 191349..191546 + 198 WP_044453281.1 YbdD/YjiX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16103.52 Da        Isoelectric Point: 7.3596

>T254186 WP_150663849.1 NZ_CP102780:186353-186772 [Pandoraea commovens]
MYLLDTNVVSESRKRGGGDEGVQRFMRMAERRRAQKFISVITMGELQRGMRVLRHRNDVRQASLIESWLEQLHIEYADDI
LPIDLTICNAWARMRVPNEQHPIDKLIAATALVHELIVVTRNVKDFSDTGVEVYNPFQP

Download         Length: 420 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7484.57 Da        Isoelectric Point: 4.5358

>AT254186 WP_150663848.1 NZ_CP102780:186138-186338 [Pandoraea commovens]
MMLIEGIDEQLMRSIESRAAQGGRTPEEEVLQILDRVARVPRFRSLGEALRAMPNVGLDSDFERIN

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References