Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 127299..127840 Replicon chromosome
Accession NZ_CP102772
Organism Bosea sp. NBC_00550

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NWE53_RS00600 Protein ID WP_265052471.1
Coordinates 127299..127622 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NWE53_RS00605 Protein ID WP_265052472.1
Coordinates 127619..127840 (-) Length 74 a.a.

Genomic Context


NWE53_RS00580NWE53_RS00585NWE53_RS00595NWE53_RS00615NWE53_RS00620NWE53_RS00625NWE53_RS00590NWE53_RS00600NWE53_RS00605NWE53_RS00610
Location: 123104..124252 (1149 bp)
Type: Others
Protein ID: WP_265052467.1
Location: 124385..125389 (1005 bp)
Type: Others
Protein ID: WP_265052468.1
Location: 125991..127274 (1284 bp)
Type: Others
Protein ID: WP_265052470.1
Location: 128936..130000 (1065 bp)
Type: Others
Protein ID: WP_265055044.1
Location: 130026..131180 (1155 bp)
Type: Others
Protein ID: WP_265052473.1
Location: 131362..132255 (894 bp)
Type: Others
Protein ID: WP_265052474.1
Location: 125390..125848 (459 bp)
Type: Others
Protein ID: WP_265052469.1
Location: 127299..127622 (324 bp)
Type: Toxin
Protein ID: WP_265052471.1
Location: 127619..127840 (222 bp)
Type: Antitoxin
Protein ID: WP_265052472.1
Location: 127913..128650 (738 bp)
Type: Others
Protein ID: WP_265055043.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NWE53_RS00580 (NWE53_00580)123104..124252+1149WP_265052467.1alpha/beta hydrolase-
NWE53_RS00585 (NWE53_00585)124385..125389+1005WP_265052468.1alpha/beta fold hydrolase-
NWE53_RS00590 (NWE53_00590)125390..125848-459WP_265052469.1Lrp/AsnC family transcriptional regulator-
NWE53_RS00595 (NWE53_00595)125991..127274+1284WP_265052470.1cystathionine gamma-synthase family protein-
NWE53_RS00600 (NWE53_00600)127299..127622-324WP_265052471.1type II toxin-antitoxin system PemK/MazF family toxinToxin
NWE53_RS00605 (NWE53_00605)127619..127840-222WP_265052472.1antitoxin MazE family proteinAntitoxin
NWE53_RS00610 (NWE53_00610)127913..128650-738WP_265055043.1DUF3750 domain-containing protein-
NWE53_RS00615 (NWE53_00615)128936..130000+1065WP_265055044.1polyamine ABC transporter substrate-binding protein-
NWE53_RS00620 (NWE53_00620)130026..131180+1155WP_265052473.1ABC transporter ATP-binding protein-
NWE53_RS00625 (NWE53_00625)131362..132255+894WP_265052474.1ABC transporter permease subunit-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-103)

Antitoxin

(7-69)


Sequences


Toxin        


Download         Length: 108 a.a.        Molecular weight: 11499.61 Da        Isoelectric Point: 10.4471

>T254184 WP_265052471.1 NZ_CP102772:c127622-127299 [Bosea sp. NBC_00550]
MKRGDLVTVALAGDFGKPRPALIVQADPFDLTATVTVLLLSSDLVDAPLIRLTIQPNAANGLRLASQIMVDKAMTVRRDR
IGQIFGRVDPDMMIAVNRSLALFLGLG

Download         Length: 324 bp


Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8130.11 Da        Isoelectric Point: 5.8189

>AT254184 WP_265052472.1 NZ_CP102772:c127840-127619 [Bosea sp. NBC_00550]
MAASTARRVQKRREALRAAGLRPIQIWIPDTRQPGFNEECRRQARMAAAADGADHDLDGFIDAALEDLDRAPE

Download         Length: 222 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References