Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3333778..3334431 Replicon chromosome
Accession NZ_CP102762
Organism Acinetobacter baumannii strain AOR07-BL

Toxin (Protein)


Gene name cptA Uniprot ID A0A9E9PBS3
Locus tag NU955_RS15755 Protein ID WP_002096593.1
Coordinates 3333778..3334167 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag NU955_RS15760 Protein ID WP_001288210.1
Coordinates 3334174..3334431 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NU955_RS15740 3328896..3331091 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
NU955_RS15745 3331279..3331845 - 567 WP_000651536.1 rhombosortase -
NU955_RS15750 3331923..3333008 - 1086 WP_000049106.1 hypothetical protein -
NU955_RS15755 3333778..3334167 - 390 WP_002096593.1 hypothetical protein Toxin
NU955_RS15760 3334174..3334431 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
NU955_RS15765 3334619..3335791 + 1173 WP_001190548.1 acyl-CoA dehydrogenase family protein -
NU955_RS15770 3335840..3337330 - 1491 WP_004745487.1 NAD(P)/FAD-dependent oxidoreductase -
NU955_RS15775 3337512..3337889 - 378 WP_001216380.1 50S ribosomal protein L17 -
NU955_RS15780 3337908..3338915 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15677.99 Da        Isoelectric Point: 10.3890

>T254158 WP_002096593.1 NZ_CP102762:c3334167-3333778 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT254158 WP_001288210.1 NZ_CP102762:c3334431-3334174 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References