Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4048526..4049076 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NV347_RS18255 Protein ID WP_039513069.1
Coordinates 4048768..4049076 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag NV347_RS18250 Protein ID WP_052237773.1
Coordinates 4048526..4048765 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS18225 (NV347_18225) 4043876..4044187 - 312 WP_103160829.1 AzlD domain-containing protein -
NV347_RS18230 (NV347_18230) 4044184..4044918 - 735 WP_103160830.1 AzlC family ABC transporter permease -
NV347_RS18235 (NV347_18235) 4045146..4045982 - 837 WP_039513064.1 AraC family transcriptional regulator -
NV347_RS18240 (NV347_18240) 4046201..4047820 - 1620 WP_039513065.1 methyl-accepting chemotaxis protein -
NV347_RS18245 (NV347_18245) 4048266..4048451 - 186 WP_039513067.1 hypothetical protein -
NV347_RS18250 (NV347_18250) 4048526..4048765 + 240 WP_052237773.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NV347_RS18255 (NV347_18255) 4048768..4049076 + 309 WP_039513069.1 CcdB family protein Toxin
NV347_RS18260 (NV347_18260) 4049219..4049383 - 165 WP_039513071.1 glucose uptake inhibitor SgrT -
NV347_RS18265 (NV347_18265) 4049474..4051132 + 1659 WP_039513074.1 HTH-type transcriptional regulator SgrR -
NV347_RS18270 (NV347_18270) 4051350..4052330 + 981 WP_165708211.1 thiamine ABC transporter substrate binding subunit -
NV347_RS18275 (NV347_18275) 4052306..4053913 + 1608 WP_039513077.1 thiamine/thiamine pyrophosphate ABC transporter permease ThiP -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11766.60 Da        Isoelectric Point: 9.3356

>T254136 WP_039513069.1 NZ_CP102749:4048768-4049076 [Pectobacterium parvum]
MQYKVYRNNGNSNSYPYLLNVQSDIIGELHTRLVIPLFPLNKVARPPARRLTPIVTVEGNDYLIMTHEMASVRRSQLGHE
VMDAQMYRKTIKDAVDFLLDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9068.43 Da        Isoelectric Point: 10.0137

>AT254136 WP_052237773.1 NZ_CP102749:4048526-4048765 [Pectobacterium parvum]
MPVTSIRHKKTVSVTLEPMLLQQAREAGINLSAILTEALKREIRLSEGEKWKQQNQKALQELNRITDKHGLLSDDDRTF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References