Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3855168..3855694 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NV347_RS17405 Protein ID WP_258210282.1
Coordinates 3855389..3855694 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID C6C380
Locus tag NV347_RS17400 Protein ID WP_015855076.1
Coordinates 3855168..3855386 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS17370 (NV347_17370) 3850504..3850635 - 132 WP_258210277.1 hypothetical protein -
NV347_RS17380 (NV347_17380) 3851380..3852639 + 1260 WP_258210278.1 integrase arm-type DNA-binding domain-containing protein -
NV347_RS17385 (NV347_17385) 3852745..3852939 - 195 WP_258210279.1 YlcI/YnfO family protein -
NV347_RS17390 (NV347_17390) 3853125..3853466 + 342 WP_258210280.1 hypothetical protein -
NV347_RS17395 (NV347_17395) 3854366..3855109 + 744 WP_258210281.1 MobC family replication-relaxation protein -
NV347_RS17400 (NV347_17400) 3855168..3855386 + 219 WP_015855076.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
NV347_RS17405 (NV347_17405) 3855389..3855694 + 306 WP_258210282.1 type II toxin-antitoxin system toxin CcdB Toxin
NV347_RS17410 (NV347_17410) 3855848..3858220 - 2373 WP_258210283.1 AAA family ATPase -
NV347_RS17415 (NV347_17415) 3858213..3858932 - 720 WP_258210284.1 hypothetical protein -
NV347_RS17420 (NV347_17420) 3858929..3860362 - 1434 WP_258210285.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3851203..3861074 9871


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11771.66 Da        Isoelectric Point: 4.5468

>T254135 WP_258210282.1 NZ_CP102749:3855389-3855694 [Pectobacterium parvum]
MQFIVYEYKRTSNYKMFVDVQSDIVETPKRRMVIPLTEAHHLSEKVNKMLFPLIRIDAEDYRLMTTELSSVPVEVIGEAI
ADLGEYADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8178.13 Da        Isoelectric Point: 7.0135

>AT254135 WP_015855076.1 NZ_CP102749:3855168-3855386 [Pectobacterium parvum]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQNGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A250BG46

References