Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 3398817..3399616 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name hepT Uniprot ID A0A6P1S6Q8
Locus tag NV347_RS15190 Protein ID WP_039482641.1
Coordinates 3399197..3399616 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID A0A6P1S5H0
Locus tag NV347_RS15185 Protein ID WP_039482638.1
Coordinates 3398817..3399200 (+) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS15170 (NV347_15170) 3394004..3395140 - 1137 WP_039482630.1 polysaccharide export protein -
NV347_RS15175 (NV347_15175) 3395260..3396357 - 1098 WP_111779044.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
NV347_RS15180 (NV347_15180) 3397091..3398677 + 1587 WP_039482635.1 TerC family protein -
NV347_RS15185 (NV347_15185) 3398817..3399200 + 384 WP_039482638.1 nucleotidyltransferase domain-containing protein Antitoxin
NV347_RS15190 (NV347_15190) 3399197..3399616 + 420 WP_039482641.1 DUF86 domain-containing protein Toxin
NV347_RS15195 (NV347_15195) 3399660..3401012 - 1353 WP_039482643.1 anaerobic C4-dicarboxylate transporter DcuC -
NV347_RS15200 (NV347_15200) 3401471..3403306 - 1836 WP_111779041.1 outer membrane assembly protein AsmA -
NV347_RS15205 (NV347_15205) 3403370..3403951 - 582 WP_039482649.1 dCTP deaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(12-129)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16138.51 Da        Isoelectric Point: 7.3845

>T254133 WP_039482641.1 NZ_CP102749:3399197-3399616 [Pectobacterium parvum]
MTDILLNKSSTIQRCLRRIREEFDTKEEFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKHLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKEVARYSDSQHL

Download         Length: 420 bp

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14312.49 Da        Isoelectric Point: 5.2241

>AT254133 WP_039482638.1 NZ_CP102749:3398817-3399200 [Pectobacterium parvum]
MFDKIVSTLKKQIPDIKIIYLFGSQATGNARADSDVDIAILATRALDPVERWELSNQLAKEVGRDVDLIDLLQASTVLKM
EIVRNGKLLYDAKAAAGEFEMTTLSMYQHLQRERADIIRSFNQDLKA

Download         Length: 384 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S6Q8

Antitoxin

Source ID Structure
AlphaFold DB A0A6P1S5H0

References