Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1845597..1846150 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NV347_RS08140 Protein ID WP_039504530.1
Coordinates 1845836..1846150 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID C6CEY1
Locus tag NV347_RS08135 Protein ID WP_012769207.1
Coordinates 1845597..1845833 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS08120 (NV347_08120) 1842292..1843239 + 948 WP_039504525.1 hypothetical protein -
NV347_RS08125 (NV347_08125) 1843309..1843812 + 504 WP_131547303.1 hypothetical protein -
NV347_RS08130 (NV347_08130) 1844333..1845277 + 945 WP_039504528.1 zincin-like metallopeptidase domain-containing protein -
NV347_RS08135 (NV347_08135) 1845597..1845833 + 237 WP_012769207.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NV347_RS08140 (NV347_08140) 1845836..1846150 + 315 WP_039504530.1 CcdB family protein Toxin
NV347_RS08145 (NV347_08145) 1846543..1847547 - 1005 WP_039504532.1 DUF4238 domain-containing protein -
NV347_RS08150 (NV347_08150) 1847650..1848636 - 987 WP_052326018.1 DUF2971 domain-containing protein -
NV347_RS08155 (NV347_08155) 1848906..1849652 - 747 WP_039504534.1 MobC family replication-relaxation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1837123..1875860 38737


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11595.59 Da        Isoelectric Point: 7.9859

>T254132 WP_039504530.1 NZ_CP102749:1845836-1846150 [Pectobacterium parvum]
MQFTVYGNTGKSVVYPLLLDVTSDIIRQLNRRIVIPLLPIEKYPAGRRPDRLVPVVMLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRSQVKAAIDFLIDGF

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9013.03 Da        Isoelectric Point: 6.4631

>AT254132 WP_012769207.1 NZ_CP102749:1845597-1845833 [Pectobacterium parvum]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLSTALDAELRRHEAKKWQEENREAIDALNRFHDENGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E4H0

References