Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1077954..1078479 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NV347_RS04760 Protein ID WP_039486183.1
Coordinates 1077954..1078238 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6D956
Locus tag NV347_RS04765 Protein ID WP_005973616.1
Coordinates 1078228..1078479 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS04745 (NV347_04745) 1074234..1075373 + 1140 WP_010681611.1 glycoside hydrolase family 88 protein -
NV347_RS04750 (NV347_04750) 1075745..1076491 - 747 WP_039486185.1 SDR family oxidoreductase -
NV347_RS04755 (NV347_04755) 1077204..1077770 + 567 WP_039513221.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
NV347_RS04760 (NV347_04760) 1077954..1078238 - 285 WP_039486183.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NV347_RS04765 (NV347_04765) 1078228..1078479 - 252 WP_005973616.1 prevent-host-death protein Antitoxin
NV347_RS04770 (NV347_04770) 1078741..1081068 - 2328 WP_258210331.1 phage/plasmid primase, P4 family -
NV347_RS04775 (NV347_04775) 1081079..1081420 - 342 WP_111778900.1 DUF5375 family protein -
NV347_RS04780 (NV347_04780) 1081417..1081683 - 267 WP_103160155.1 hypothetical protein -
NV347_RS04785 (NV347_04785) 1081680..1081874 - 195 WP_005973630.1 hypothetical protein -
NV347_RS04790 (NV347_04790) 1081867..1082064 - 198 WP_121266703.1 host cell division inhibitor Icd-like protein -
NV347_RS04795 (NV347_04795) 1082100..1082411 - 312 Protein_927 ash family protein -
NV347_RS04800 (NV347_04800) 1082420..1082644 - 225 WP_015841426.1 hypothetical protein -
NV347_RS04805 (NV347_04805) 1082641..1082865 - 225 WP_165707587.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11010.02 Da        Isoelectric Point: 10.3917

>T254130 WP_039486183.1 NZ_CP102749:c1078238-1077954 [Pectobacterium parvum]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVIKHEIVVLVLAVGK
RERSEVYKTAKDRL

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9079.35 Da        Isoelectric Point: 5.0807

>AT254130 WP_005973616.1 NZ_CP102749:c1078479-1078228 [Pectobacterium parvum]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G4JQP6

References