Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 772888..773548 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name cptA Uniprot ID A0A093S6F1
Locus tag NV347_RS03480 Protein ID WP_039487287.1
Coordinates 773135..773548 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A093SCR9
Locus tag NV347_RS03475 Protein ID WP_039487284.1
Coordinates 772888..773154 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS03455 (NV347_03455) 768744..769748 - 1005 WP_039487278.1 substrate-binding domain-containing protein -
NV347_RS03460 (NV347_03460) 769803..770411 - 609 WP_039487279.1 HD domain-containing protein -
NV347_RS03465 (NV347_03465) 770812..771459 + 648 WP_039487281.1 hemolysin III family protein -
NV347_RS03470 (NV347_03470) 771651..772652 - 1002 WP_039487282.1 tRNA-modifying protein YgfZ -
NV347_RS03475 (NV347_03475) 772888..773154 + 267 WP_039487284.1 FAD assembly factor SdhE Antitoxin
NV347_RS03480 (NV347_03480) 773135..773548 + 414 WP_039487287.1 protein YgfX Toxin
NV347_RS03485 (NV347_03485) 773617..774552 + 936 WP_039487289.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
NV347_RS03490 (NV347_03490) 774618..774941 - 324 WP_039487292.1 hypothetical protein -
NV347_RS03495 (NV347_03495) 774970..775488 - 519 WP_039487295.1 flavodoxin FldB -
NV347_RS03500 (NV347_03500) 775820..776206 - 387 WP_039282122.1 thioesterase family protein -
NV347_RS03505 (NV347_03505) 776431..777753 - 1323 WP_039487297.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16297.28 Da        Isoelectric Point: 10.6913

>T254129 WP_039487287.1 NZ_CP102749:773135-773548 [Pectobacterium parvum]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQKNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLRAVNGKDKQQLWLASDSMGDEEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10489.90 Da        Isoelectric Point: 5.1392

>AT254129 WP_039487284.1 NZ_CP102749:772888-773154 [Pectobacterium parvum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRIISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A093S6F1

Antitoxin

Source ID Structure
AlphaFold DB A0A093SCR9

References