Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | sdenTA/AbiEii(toxin) |
| Location | 333868..335308 | Replicon | chromosome |
| Accession | NZ_CP102749 | ||
| Organism | Pectobacterium parvum strain YT22221 | ||
Toxin (Protein)
| Gene name | sdenT | Uniprot ID | - |
| Locus tag | NV347_RS01455 | Protein ID | WP_161546756.1 |
| Coordinates | 334421..335308 (+) | Length | 296 a.a. |
Antitoxin (Protein)
| Gene name | sdenA | Uniprot ID | A0A6P1S3G1 |
| Locus tag | NV347_RS01450 | Protein ID | WP_039483130.1 |
| Coordinates | 333868..334392 (+) | Length | 175 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NV347_RS01430 (NV347_01430) | 329882..332371 | + | 2490 | WP_161546755.1 | restriction endonuclease-like protein | - |
| NV347_RS01435 (NV347_01435) | 332557..333381 | - | 825 | WP_249642132.1 | DNA damage-inducible protein D | - |
| NV347_RS01440 (NV347_01440) | 333577..333663 | + | 87 | Protein_281 | integrase | - |
| NV347_RS01445 (NV347_01445) | 333672..333758 | - | 87 | Protein_282 | hypothetical protein | - |
| NV347_RS01450 (NV347_01450) | 333868..334392 | + | 525 | WP_039483130.1 | hypothetical protein | Antitoxin |
| NV347_RS01455 (NV347_01455) | 334421..335308 | + | 888 | WP_161546756.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| NV347_RS01460 (NV347_01460) | 335414..336277 | - | 864 | WP_039483124.1 | YicC/YloC family endoribonuclease | - |
| NV347_RS01465 (NV347_01465) | 336376..337284 | - | 909 | WP_039483122.1 | LysR family transcriptional regulator | - |
| NV347_RS01470 (NV347_01470) | 337498..338445 | - | 948 | WP_258210313.1 | isoaspartyl peptidase/L-asparaginase | - |
| NV347_RS01475 (NV347_01475) | 338505..339326 | - | 822 | WP_039483117.1 | M55 family metallopeptidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 326486..335308 | 8822 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 296 a.a. Molecular weight: 34051.03 Da Isoelectric Point: 5.7136
>T254127 WP_161546756.1 NZ_CP102749:334421-335308 [Pectobacterium parvum]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDFPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIIWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKPIKERTLDNPEYWAYVQGEVHAIASELLNDGIPKNPFDMG
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDFPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIIWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKPIKERTLDNPEYWAYVQGEVHAIASELLNDGIPKNPFDMG
Download Length: 888 bp
Antitoxin
Download Length: 175 a.a. Molecular weight: 19369.51 Da Isoelectric Point: 9.0504
>AT254127 WP_039483130.1 NZ_CP102749:333868-334392 [Pectobacterium parvum]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSSVLSYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSSVLSYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
Download Length: 525 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|