Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1408605..1409230 Replicon chromosome
Accession NZ_CP102747
Organism Streptococcus parasuis strain SFJ45

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NWE22_RS07205 Protein ID WP_171989763.1
Coordinates 1408605..1408943 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NWE22_RS07210 Protein ID WP_130554939.1
Coordinates 1408943..1409230 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWE22_RS07180 (NWE22_07180) 1404496..1405470 - 975 WP_274512952.1 YvcK family protein -
NWE22_RS07185 (NWE22_07185) 1405467..1406354 - 888 WP_277745295.1 RNase adapter RapZ -
NWE22_RS07190 (NWE22_07190) 1406377..1406757 - 381 WP_130554943.1 RidA family protein -
NWE22_RS07195 (NWE22_07195) 1406807..1408126 - 1320 WP_277745296.1 MATE family efflux transporter -
NWE22_RS07200 (NWE22_07200) 1408421..1408624 - 204 WP_277745297.1 LPXTG cell wall anchor domain-containing protein -
NWE22_RS07205 (NWE22_07205) 1408605..1408943 - 339 WP_171989763.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NWE22_RS07210 (NWE22_07210) 1408943..1409230 - 288 WP_130554939.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NWE22_RS07215 (NWE22_07215) 1409378..1409647 - 270 WP_105127516.1 type II toxin-antitoxin system RelE/ParE family toxin -
NWE22_RS07220 (NWE22_07220) 1409637..1409864 - 228 WP_130554954.1 DUF6290 family protein -
NWE22_RS07225 (NWE22_07225) 1410202..1411548 - 1347 WP_277745298.1 asparagine--tRNA ligase -
NWE22_RS07230 (NWE22_07230) 1411563..1412744 - 1182 WP_277745299.1 pyridoxal phosphate-dependent aminotransferase -
NWE22_RS07235 (NWE22_07235) 1412741..1413238 - 498 WP_277745300.1 DUF5590 domain-containing protein -
NWE22_RS07240 (NWE22_07240) 1413385..1413825 + 441 WP_277745301.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-106)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(10-81)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12914.84 Da        Isoelectric Point: 5.9262

>T254115 WP_171989763.1 NZ_CP102747:c1408943-1408605 [Streptococcus parasuis]
MEKYRVIISPKLIEQIKSIRDYVANVKLSPETAERLVTAIFDEIESLELFPERGFDADEKIGVKIDKNGRSSRGITIQNG
KYIVIYTVNQEEHLVEVAFLFSSKTDYAKLFR

Download         Length: 339 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10811.34 Da        Isoelectric Point: 4.7494

>AT254115 WP_130554939.1 NZ_CP102747:c1409230-1408943 [Streptococcus parasuis]
MPTVIRDKQINFKVNSEYFELAKVVFQENGLDITSAFNEFVQEVAISKTLPFKTVEEKEREKLIARLQEEVSTSYEALKA
DKGLSVEEARKAVLG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References