Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 511351..511865 Replicon chromosome
Accession NZ_CP102745
Organism Ornithobacterium rhinotracheale strain IRI-Sh

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NV236_RS02440 Protein ID WP_258205062.1
Coordinates 511351..511608 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NV236_RS02445 Protein ID WP_258204953.1
Coordinates 511611..511865 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV236_RS02400 (NV236_02400) 506406..507233 + 828 WP_014791214.1 50S ribosomal protein L11 methyltransferase -
NV236_RS02405 (NV236_02405) 507237..507530 + 294 WP_014791213.1 ATP-dependent Clp protease adaptor ClpS -
NV236_RS02410 (NV236_02410) 507545..507958 + 414 WP_155814511.1 Holliday junction resolvase RuvX -
NV236_RS02415 (NV236_02415) 508109..508681 + 573 WP_014791211.1 peptide deformylase -
NV236_RS02420 (NV236_02420) 508731..509156 + 426 WP_014791210.1 DUF5606 domain-containing protein -
NV236_RS02425 (NV236_02425) 509245..510018 + 774 WP_014791209.1 nucleoside triphosphate pyrophosphohydrolase -
NV236_RS02430 (NV236_02430) 510070..510996 + 927 WP_014791208.1 J domain-containing protein -
NV236_RS02435 (NV236_02435) 511002..511295 + 294 WP_014791207.1 chaperone modulator CbpM -
NV236_RS02440 (NV236_02440) 511351..511608 - 258 WP_258205062.1 Txe/YoeB family addiction module toxin Toxin
NV236_RS02445 (NV236_02445) 511611..511865 - 255 WP_258204953.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NV236_RS02450 (NV236_02450) 511937..514168 - 2232 WP_258204954.1 TonB-dependent receptor -
NV236_RS02455 (NV236_02455) 514149..515516 - 1368 WP_014791203.1 HTTM domain-containing protein -
NV236_RS02460 (NV236_02460) 515543..516670 - 1128 WP_014791202.1 imelysin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10573.14 Da        Isoelectric Point: 8.9288

>T254107 WP_258205062.1 NZ_CP102745:c511608-511351 [Ornithobacterium rhinotracheale]
IKYIFVDESWEDYLYWQKNDKRKLKRINALLKDISRTPFEGIGKPEPLKHKYSGFWSRRIDDEHCLIYRYEEDKILIAKC
RFHYD

Download         Length: 258 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9568.92 Da        Isoelectric Point: 5.8524

>AT254107 WP_258204953.1 NZ_CP102745:c511865-511611 [Ornithobacterium rhinotracheale]
MLVTNISEFRKDLKSYLNKVAKNFETLIINRGKESAIVVLSLDEYNSLMATNYELSSRKNEQHLDAAIAKLKSGESFEKT
LIED

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References