Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1890248..1890393 Replicon chromosome
Accession NZ_CP102692
Organism Klebsiella pneumoniae strain GN4542

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1890284..1890386 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1890248..1890393 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV951_RS09180 (NV951_09180) 1885378..1887438 + 2061 WP_004151449.1 oligopeptidase B -
NV951_RS09185 (NV951_09185) 1887442..1888101 - 660 WP_002911407.1 exodeoxyribonuclease X -
NV951_RS09190 (NV951_09190) 1888180..1888410 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NV951_RS09195 (NV951_09195) 1888523..1888897 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NV951_RS09200 (NV951_09200) 1888901..1889770 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NV951_RS09205 (NV951_09205) 1889787..1890125 + 339 WP_002911404.1 YebY family protein -
- 1890248..1890393 - 146 - - Antitoxin
- 1890284..1890386 + 103 - - Toxin
NV951_RS09210 (NV951_09210) 1890762..1890905 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
NV951_RS09215 (NV951_09215) 1891010..1891978 - 969 WP_074182211.1 VirK/YbjX family protein -
NV951_RS09220 (NV951_09220) 1892135..1892788 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
NV951_RS09225 (NV951_09225) 1892785..1892976 - 192 WP_002911395.1 YebW family protein -
NV951_RS09230 (NV951_09230) 1893074..1893313 - 240 WP_002911393.1 YebV family protein -
NV951_RS09235 (NV951_09235) 1893429..1894862 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T254019 NZ_CP102692:1890284-1890386 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT254019 NZ_CP102692:c1890393-1890248 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References