Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 184275..184419 | Replicon | chromosome |
| Accession | NZ_CP102687 | ||
| Organism | Klebsiella pneumoniae strain GN4539 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 184311..184413 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 184275..184419 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NV950_RS00860 (NV950_00860) | 179405..181465 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NV950_RS00865 (NV950_00865) | 181469..182128 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NV950_RS00870 (NV950_00870) | 182207..182437 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NV950_RS00875 (NV950_00875) | 182550..182924 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NV950_RS00880 (NV950_00880) | 182928..183797 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| NV950_RS00885 (NV950_00885) | 183814..184152 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 184275..184419 | - | 145 | - | - | Antitoxin |
| - | 184311..184413 | + | 103 | - | - | Toxin |
| NV950_RS00890 (NV950_00890) | 184546..184827 | - | 282 | Protein_169 | tyrosine-type recombinase/integrase | - |
| NV950_RS00895 (NV950_00895) | 184904..185383 | + | 480 | WP_032419797.1 | lysis protein | - |
| NV950_RS00900 (NV950_00900) | 185838..186033 | + | 196 | Protein_171 | DNA polymerase V | - |
| NV950_RS00905 (NV950_00905) | 186172..187677 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| NV950_RS00910 (NV950_00910) | 187927..188355 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NV950_RS00915 (NV950_00915) | 188365..188646 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T254000 NZ_CP102687:184311-184413 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT254000 NZ_CP102687:c184419-184275 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
