253926

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 61788..62413 Replicon plasmid unnamed
Accession NZ_CP102670
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain ATCC 14028

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NUW86_RS24690 Protein ID WP_000911322.1
Coordinates 61788..62186 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NUW86_RS24695 Protein ID WP_000450265.1
Coordinates 62186..62413 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUW86_RS24675 (NUW86_24675) 57979..58473 + 495 WP_010999946.1 entry exclusion protein -
NUW86_RS24680 (NUW86_24680) 58509..59240 + 732 WP_000782438.1 conjugal transfer complement resistance protein TraT -
NUW86_RS24685 (NUW86_24685) 59617..61779 + 2163 WP_000009318.1 type IV conjugative transfer system coupling protein TraD -
NUW86_RS24690 (NUW86_24690) 61788..62186 - 399 WP_000911322.1 type II toxin-antitoxin system VapC family toxin Toxin
NUW86_RS24695 (NUW86_24695) 62186..62413 - 228 WP_000450265.1 toxin-antitoxin system antitoxin VapB Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - fdeC / spvC / spvB / rck / pefD / pefC / pefA / pefB 1..93832 93832


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14887.13 Da        Isoelectric Point: 8.5264

>T253926 WP_000911322.1 NZ_CP102670:c62186-61788 [Salmonella enterica subsp. enterica serovar Typhimurium]
MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELIYGAEKSQMPERNLAVIEGFVSRLDVLDYDTPAATHT
GQIRAELARQGRPVGPFDQMIAGHARSRGLIVVTNNTREFERVGGLRTEDWS

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8509.49 Da        Isoelectric Point: 4.5358

>AT253926 WP_000450265.1 NZ_CP102670:c62413-62186 [Salmonella enterica subsp. enterica serovar Typhimurium]
METSVFLSNRSQAVRLPKAVALPENVKRVEVIAVGRTRIITPAGESWDEWFDGNNVSADFMDNREQPSVQERESF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References