Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 201604..202163 Replicon chromosome
Accession NZ_CP102665
Organism Sphingobium sp. JS3065

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NUH86_RS18405 Protein ID WP_267252773.1
Coordinates 201870..202163 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NUH86_RS18400 Protein ID WP_267252772.1
Coordinates 201604..201873 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUH86_RS18370 (NUH86_18375) 196973..197527 - 555 WP_267252766.1 hypothetical protein -
NUH86_RS18375 (NUH86_18380) 197572..197739 + 168 WP_267252767.1 hypothetical protein -
NUH86_RS18380 (NUH86_18385) 197905..199428 + 1524 WP_267252768.1 IS21 family transposase -
NUH86_RS18385 (NUH86_18390) 199418..200200 + 783 WP_267252769.1 IS21-like element helper ATPase IstB -
NUH86_RS18390 (NUH86_18395) 200262..200840 - 579 WP_267252770.1 hypothetical protein -
NUH86_RS18395 (NUH86_18400) 200907..201224 - 318 WP_267252771.1 hypothetical protein -
NUH86_RS18400 (NUH86_18405) 201604..201873 + 270 WP_267252772.1 ribbon-helix-helix domain-containing protein Antitoxin
NUH86_RS18405 (NUH86_18410) 201870..202163 + 294 WP_267252773.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NUH86_RS18410 (NUH86_18415) 202207..202377 - 171 WP_267252774.1 hypothetical protein -
NUH86_RS18415 (NUH86_18420) 202422..204326 - 1905 WP_267252775.1 plasmid recombination protein -
NUH86_RS18420 (NUH86_18425) 204557..205045 - 489 WP_267252776.1 hypothetical protein -
NUH86_RS18425 (NUH86_18430) 205967..206617 + 651 WP_267252777.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 201328..221284 19956


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11449.15 Da        Isoelectric Point: 9.0138

>T253903 WP_267252773.1 NZ_CP102665:201870-202163 [Sphingobium sp. JS3065]
MKIQWTSKASSDLLRLHEHLRPVAPEAAARVVQQLAHAPNRLLDYPRLGEKLEAFEPREVRRIIVGNYEMRYEIASGTIF
ILRLWHCRENRSFESEH

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9673.92 Da        Isoelectric Point: 4.7734

>AT253903 WP_267252772.1 NZ_CP102665:201604-201873 [Sphingobium sp. JS3065]
MAAATRVLTAHVPEGLADKVDALAARIERSRGWIMKQALAAWIDQEEERHKMTLEALADVDAGRVIDHQSIQAWADSLST
DSPLPSPTA

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References