Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1681874..1682673 Replicon chromosome
Accession NZ_CP102664
Organism Sphingobium sp. JS3065

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NUH86_RS08030 Protein ID WP_267251930.1
Coordinates 1682170..1682673 (+) Length 168 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID N1MNI2
Locus tag NUH86_RS08025 Protein ID WP_006960007.1
Coordinates 1681874..1682161 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUH86_RS08015 (NUH86_08015) 1677406..1681149 + 3744 WP_267251928.1 conjugal transfer protein TraG N-terminal domain-containing protein -
NUH86_RS08020 (NUH86_08020) 1681146..1681679 - 534 WP_267251929.1 hypothetical protein -
NUH86_RS08025 (NUH86_08025) 1681874..1682161 + 288 WP_006960007.1 DUF1778 domain-containing protein Antitoxin
NUH86_RS08030 (NUH86_08030) 1682170..1682673 + 504 WP_267251930.1 GNAT family N-acetyltransferase Toxin
NUH86_RS08035 (NUH86_08035) 1682700..1683614 + 915 WP_267251931.1 HEPN domain-containing protein -
NUH86_RS08040 (NUH86_08040) 1683718..1686705 + 2988 WP_267251932.1 RelA/SpoT domain-containing protein -
NUH86_RS08045 (NUH86_08045) 1686738..1687313 - 576 WP_267251933.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-144)

Antitoxin

Vibrio phage ICP1, Orf50

(4-92)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18448.02 Da        Isoelectric Point: 8.9296

>T253901 WP_267251930.1 NZ_CP102664:1682170-1682673 [Sphingobium sp. JS3065]
MAPQFRIEKLRRDHAIDVFDCGREELNRFLSRYAWQAQQGGASQSYVALTGDEVVGFHTLVVGHVDHSDAPDRLTKGMAR
HPVPLMILARLGVSTGYQGKGLGSGLLKDALTRTLQAADIAGIRAIAAHAKDEAARQFYQNFDFIPGLSDPNHMFLLLKD
ARRHLQG

Download         Length: 504 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10466.82 Da        Isoelectric Point: 5.7066

>AT253901 WP_006960007.1 NZ_CP102664:1681874-1682161 [Sphingobium sp. JS3065]
MASATARTEKLDLRLSPTAKRTLQQAALAAHRSVSEFVLESALARAEETLPDRREFNLDADQWAAFLAALDAPPRHTPRL
AELLTKPSVFEQDPG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N1MNI2

References