253890

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 2574065..2574681 Replicon chromosome
Accession NZ_CP102604
Organism Pantoea sp. SOD02

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NR302_RS12025 Protein ID WP_258143556.1
Coordinates 2574493..2574681 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NR302_RS12020 Protein ID WP_258143555.1
Coordinates 2574065..2574475 (-) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NR302_RS12000 (NR302_12000) 2569992..2570819 - 828 WP_179450225.1 MetQ/NlpA family lipoprotein -
NR302_RS12005 (NR302_12005) 2571033..2571674 + 642 WP_258143553.1 TetR family transcriptional regulator -
NR302_RS12010 (NR302_12010) 2571749..2573131 + 1383 WP_258143554.1 D-arabinono-1,4-lactone oxidase -
NR302_RS12015 (NR302_12015) 2573150..2573977 + 828 WP_061717669.1 glycosyltransferase family 8 protein -
NR302_RS12020 (NR302_12020) 2574065..2574475 - 411 WP_258143555.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NR302_RS12025 (NR302_12025) 2574493..2574681 - 189 WP_258143556.1 type II toxin-antitoxin system HicA family toxin Toxin
NR302_RS12030 (NR302_12030) 2574826..2575146 - 321 WP_008110563.1 PTS system regulator TmaR -
NR302_RS12035 (NR302_12035) 2575308..2576366 - 1059 WP_008110562.1 FUSC family protein -
NR302_RS12040 (NR302_12040) 2576729..2577193 - 465 WP_258143557.1 GyrI-like domain-containing protein -
NR302_RS12045 (NR302_12045) 2577282..2578448 - 1167 WP_258143558.1 serine-type D-Ala-D-Ala carboxypeptidase DacD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-128)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 6970.23 Da        Isoelectric Point: 11.0007

>T253890 WP_258143556.1 NZ_CP102604:c2574681-2574493 [Pantoea sp. SOD02]
MDSRSLMAEIKADGWELIRVNGSHHHFVHPVKKGLVTIPHPKKDLPVKTVKSIRKQAGLTVH

Download         Length: 189 bp

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 14785.11 Da        Isoelectric Point: 4.5951

>AT253890 WP_258143555.1 NZ_CP102604:c2574475-2574065 [Pantoea sp. SOD02]
MFYPIAIEAGDQSTAFGVTVPDLPGCFSAGDTLEAAVKNAKEAIIGHLELLVELEQDIPAVSELKSLMKDPQYAGYVWVL
IDVDVTRILGGSEKINVTLPKLLIDRIDRCVATHPEFKTRSGFLAQVALERIAKTS

Download         Length: 411 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References