253889

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 1698478..1699096 Replicon chromosome
Accession NZ_CP102604
Organism Pantoea sp. SOD02

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NR302_RS07895 Protein ID WP_036649445.1
Coordinates 1698914..1699096 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NR302_RS07890 Protein ID WP_154152625.1
Coordinates 1698478..1698873 (-) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NR302_RS07870 (NR302_07870) 1694271..1695683 - 1413 WP_258144947.1 hypothetical protein -
NR302_RS07875 (NR302_07875) 1695676..1696590 - 915 WP_154152634.1 glycosyltransferase family 2 protein -
NR302_RS07880 (NR302_07880) 1696598..1696945 - 348 Protein_1527 GtrA family protein -
NR302_RS07885 (NR302_07885) 1697122..1698378 - 1257 WP_061716806.1 mechanosensitive ion channel -
NR302_RS07890 (NR302_07890) 1698478..1698873 - 396 WP_154152625.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NR302_RS07895 (NR302_07895) 1698914..1699096 - 183 WP_036649445.1 type II toxin-antitoxin system HicA family toxin Toxin
NR302_RS07900 (NR302_07900) 1699367..1699564 + 198 WP_008108184.1 DUF6404 family protein -
NR302_RS07905 (NR302_07905) 1699666..1699860 + 195 WP_258144948.1 hypothetical protein -
NR302_RS07910 (NR302_07910) 1699889..1700137 - 249 WP_007891510.1 CsbD family protein -
NR302_RS07915 (NR302_07915) 1700286..1700837 - 552 WP_258144949.1 hypothetical protein -
NR302_RS07920 (NR302_07920) 1700899..1701228 - 330 WP_008108186.1 hypothetical protein -
NR302_RS07925 (NR302_07925) 1701428..1701607 + 180 WP_008108187.1 hypothetical protein -
NR302_RS07930 (NR302_07930) 1701737..1702120 + 384 WP_008108188.1 hypothetical protein -
NR302_RS07935 (NR302_07935) 1702122..1702796 - 675 WP_008108190.1 MBL fold metallo-hydrolase -
NR302_RS07940 (NR302_07940) 1702820..1703743 - 924 WP_258144950.1 muramoyltetrapeptide carboxypeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-124)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6932.18 Da        Isoelectric Point: 10.6249

>T253889 WP_036649445.1 NZ_CP102604:c1699096-1698914 [Pantoea sp. SOD02]
MKSSELIKMLVNTGWSLERIKGSHHQFSHPDFSYLITVPHPRKDLKTGTLMQILKDAKLK

Download         Length: 183 bp

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14681.49 Da        Isoelectric Point: 4.4315

>AT253889 WP_154152625.1 NZ_CP102604:c1698873-1698478 [Pantoea sp. SOD02]
MLYPAFVEIDVDGSASGFFPDVTGCYFAGDTPEHTLYDAQSALSAHFELMAEKSMLIPEPSQNWITDFSQTGIWIYVEID
ITRYLGKSERINITMPNLLIEKIDQAVGNDARYNSRSHFLAEAARKALSHS

Download         Length: 396 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References