253888

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1130802..1131422 Replicon chromosome
Accession NZ_CP102604
Organism Pantoea sp. SOD02

Toxin (Protein)


Gene name Hha Uniprot ID J2UI73
Locus tag NR302_RS05145 Protein ID WP_007886938.1
Coordinates 1130802..1131020 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID J3DFW0
Locus tag NR302_RS05150 Protein ID WP_007886936.1
Coordinates 1131045..1131422 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NR302_RS05115 (NR302_05115) 1126582..1126920 + 339 WP_007886947.1 P-II family nitrogen regulator -
NR302_RS05120 (NR302_05120) 1126954..1128243 + 1290 WP_008103907.1 ammonium transporter AmtB -
NR302_RS05125 (NR302_05125) 1128315..1129178 - 864 WP_258144712.1 acyl-CoA thioesterase II -
NR302_RS05130 (NR302_05130) 1129384..1129941 + 558 WP_008103903.1 YbaY family lipoprotein -
NR302_RS05135 (NR302_05135) 1130087..1130398 - 312 WP_008103902.1 MGMT family protein -
NR302_RS05145 (NR302_05145) 1130802..1131020 - 219 WP_007886938.1 HHA domain-containing protein Toxin
NR302_RS05150 (NR302_05150) 1131045..1131422 - 378 WP_007886936.1 Hha toxicity modulator TomB Antitoxin
NR302_RS05155 (NR302_05155) 1131570..1131923 - 354 WP_154153581.1 hypothetical protein -
NR302_RS05160 (NR302_05160) 1132264..1132920 + 657 WP_258144713.1 ABC transporter ATP-binding protein -
NR302_RS05165 (NR302_05165) 1132917..1133756 + 840 WP_258144714.1 metal ABC transporter permease -
NR302_RS05170 (NR302_05170) 1133779..1134657 + 879 WP_258144715.1 metal ABC transporter substrate-binding protein -
NR302_RS05175 (NR302_05175) 1134702..1134842 - 141 WP_008103894.1 type B 50S ribosomal protein L36 -
NR302_RS05180 (NR302_05180) 1134858..1135115 - 258 WP_008103892.1 type B 50S ribosomal protein L31 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8594.98 Da        Isoelectric Point: 9.5023

>T253888 WP_007886938.1 NZ_CP102604:c1131020-1130802 [Pantoea sp. SOD02]
MSNQALTKTDYLMRLRRCRSIDTLERVIEKNKYELPDNELAVFYSAADHRLAELTMNKLYDKVPVSVWKFVR

Download         Length: 219 bp

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14743.36 Da        Isoelectric Point: 4.4069

>AT253888 WP_007886936.1 NZ_CP102604:c1131422-1131045 [Pantoea sp. SOD02]
MDEYSPKRHDIAQLKYLCENLFDESMATLTDSHHGWVNDPTSESNLQLNDLIEHIASFTMNYKIKHVEDEALITQIDEYL
DDTFMLFSSYGINTQDLQRWQRSAKRLFNLFAEECAYLQQPSHSF

Download         Length: 378 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2M9WAL0

Antitoxin

Source ID Structure
AlphaFold DB J3DFW0

References