Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4574726..4575066 Replicon chromosome
Accession NZ_CP102594
Organism Xanthomonas sp. CFBP 8445

Toxin (Protein)


Gene name EcnB Uniprot ID -
Locus tag NUG21_RS19820 Protein ID WP_010341024.1
Coordinates 4574726..4574860 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A2P5Z6F1
Locus tag NUG21_RS19825 Protein ID WP_010341023.1
Coordinates 4574914..4575066 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG21_RS19795 (NUG21_19795) 4570469..4570636 - 168 WP_242085008.1 peptidase -
NUG21_RS19800 (NUG21_19800) 4570744..4571676 - 933 WP_263391803.1 MBL fold metallo-hydrolase -
NUG21_RS19805 (NUG21_19805) 4571903..4573195 - 1293 WP_263391804.1 tryptophan--tRNA ligase -
NUG21_RS19810 (NUG21_19810) 4573305..4574255 + 951 WP_263391805.1 hypothetical protein -
NUG21_RS19815 (NUG21_19815) 4574327..4574542 - 216 WP_010341025.1 CsbD family protein -
NUG21_RS19820 (NUG21_19820) 4574726..4574860 - 135 WP_010341024.1 entericidin A/B family lipoprotein Toxin
NUG21_RS19825 (NUG21_19825) 4574914..4575066 - 153 WP_010341023.1 entericidin A/B family lipoprotein Antitoxin
NUG21_RS19830 (NUG21_19830) 4575208..4576131 - 924 WP_160946089.1 arginase -
NUG21_RS19835 (NUG21_19835) 4576513..4576848 + 336 WP_263391806.1 hypothetical protein -
NUG21_RS19845 (NUG21_19845) 4577292..4578134 - 843 WP_263391807.1 SPOR domain-containing protein -
NUG21_RS19850 (NUG21_19850) 4578232..4578969 - 738 WP_263391808.1 type III pantothenate kinase -
NUG21_RS19855 (NUG21_19855) 4578966..4579943 - 978 WP_263391809.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4645.45 Da        Isoelectric Point: 9.2977

>T253880 WP_010341024.1 NZ_CP102594:c4574860-4574726 [Xanthomonas sp. CFBP 8445]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVQKAGEKVEDAAKN

Download         Length: 135 bp

>T253880 NZ_CP102594:c4574860-4574726 [Xanthomonas sp. CFBP 8445]
ATGAAGCGTACATTTGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCCGGCTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCGGGCGAGAAGGTCGAAGACGCTGCCAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5208.16 Da        Isoelectric Point: 8.1219

>AT253880 WP_010341023.1 NZ_CP102594:c4575066-4574914 [Xanthomonas sp. CFBP 8445]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDKAQDCSAGKC

Download         Length: 153 bp

>AT253880 NZ_CP102594:c4575066-4574914 [Xanthomonas sp. CFBP 8445]
ATGAAGCGACTGACCACCCTGTTGATGCTGACCCTGTTCTGCGCTGGCGTGCTGACCGGCTGCAACACCGTTGCCGGCGC
CGGCAAGGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACAAGGCGCAGGATTGCAGCGCTGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2P5Z6F1

References