Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3619902..3620407 Replicon chromosome
Accession NZ_CP102594
Organism Xanthomonas sp. CFBP 8445

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NUG21_RS15395 Protein ID WP_263391329.1
Coordinates 3620150..3620407 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6N7Q778
Locus tag NUG21_RS15390 Protein ID WP_017907919.1
Coordinates 3619902..3620153 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG21_RS15375 (NUG21_15375) 3617603..3618052 - 450 WP_263391326.1 nuclear transport factor 2 family protein -
NUG21_RS15380 (NUG21_15380) 3618174..3618899 + 726 WP_263391327.1 helix-turn-helix transcriptional regulator -
NUG21_RS15385 (NUG21_15385) 3618987..3619745 - 759 WP_263391328.1 endonuclease -
NUG21_RS15390 (NUG21_15390) 3619902..3620153 + 252 WP_017907919.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NUG21_RS15395 (NUG21_15395) 3620150..3620407 + 258 WP_263391329.1 Txe/YoeB family addiction module toxin Toxin
NUG21_RS15405 (NUG21_15405) 3620672..3621025 - 354 WP_010342469.1 PilZ domain-containing protein -
NUG21_RS15410 (NUG21_15410) 3621022..3621984 - 963 WP_160946373.1 DNA polymerase III subunit delta' -
NUG21_RS15415 (NUG21_15415) 3621981..3622652 - 672 WP_263391330.1 dTMP kinase -
NUG21_RS15420 (NUG21_15420) 3622649..3623716 - 1068 WP_263391331.1 endolytic transglycosylase MltG -
NUG21_RS15425 (NUG21_15425) 3623785..3625134 - 1350 WP_263391332.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10237.77 Da        Isoelectric Point: 9.6589

>T253879 WP_263391329.1 NZ_CP102594:3620150-3620407 [Xanthomonas sp. CFBP 8445]
VTLQFSDNAWEDYLYWQQADKKMLKRINDLIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIIYKVEHGVLLIAQV
RYHYV

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9324.59 Da        Isoelectric Point: 5.1186

>AT253879 WP_017907919.1 NZ_CP102594:3619902-3620153 [Xanthomonas sp. CFBP 8445]
MDTITYSAARAALADTMDRVVNNHEPVIITRSREQAVVMLSLEDYKAMEETAYLLRSPKNAQRLLESIAQLESGRGKARE
LSE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7Q778

References