Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicA
Location 4788593..4789005 Replicon chromosome
Accession NZ_CP102593
Organism Xanthomonas campestris pv. phormiicola strain CFBP 8444

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NRY95_RS20225 Protein ID WP_191826298.1
Coordinates 4788811..4789005 (-) Length 65 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NRY95_RS20220 Protein ID WP_228318337.1
Coordinates 4788593..4788805 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRY95_RS20205 (NRY95_20210) 4784024..4784512 + 489 WP_228318340.1 DUF4065 domain-containing protein -
NRY95_RS20210 (NRY95_20215) 4784530..4785252 + 723 WP_228318339.1 hypothetical protein -
NRY95_RS20215 (NRY95_20220) 4786147..4788306 - 2160 WP_228318338.1 ATP-binding domain-containing protein -
NRY95_RS20220 (NRY95_20225) 4788593..4788805 - 213 WP_228318337.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NRY95_RS20225 (NRY95_20230) 4788811..4789005 - 195 WP_191826298.1 type II toxin-antitoxin system HicA family toxin Toxin
NRY95_RS20230 (NRY95_20235) 4789118..4791808 - 2691 WP_228318336.1 pyruvate dehydrogenase (acetyl-transferring), homodimeric type -
NRY95_RS20235 (NRY95_20240) 4792010..4793986 + 1977 WP_228318335.1 SpoIIE family protein phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4775007..4799061 24054


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-62)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-62)


Sequences

Toxin        


Download         Length: 65 a.a.        Molecular weight: 7061.10 Da        Isoelectric Point: 11.2875

>T253877 WP_191826298.1 NZ_CP102593:c4789005-4788811 [Xanthomonas campestris pv. phormiicola]
MPPKIRDVLQQLRDAGWQQVSQTGSHRQFKHPVYPGRVTVAGKPSDDVAPGTLNSILKQAGLKR

Download         Length: 195 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7479.39 Da        Isoelectric Point: 3.7917

>AT253877 WP_228318337.1 NZ_CP102593:c4788805-4788593 [Xanthomonas campestris pv. phormiicola]
MRYAVVIEQAGNNYSAYVPDLPGCVATGATTAEVEDLIREAIELHLAGMREDGEVIPLPSSQVEYVDVAA

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References