Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966077..1966222 Replicon chromosome
Accession NZ_CP102552
Organism Klebsiella pneumoniae strain KPH3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966113..1966215 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966077..1966222 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG48_RS09705 (NUG48_09705) 1961207..1963267 + 2061 WP_004151449.1 oligopeptidase B -
NUG48_RS09710 (NUG48_09710) 1963271..1963930 - 660 WP_002911407.1 exodeoxyribonuclease X -
NUG48_RS09715 (NUG48_09715) 1964009..1964239 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NUG48_RS09720 (NUG48_09720) 1964352..1964726 + 375 WP_039819395.1 CopC domain-containing protein YobA -
NUG48_RS09725 (NUG48_09725) 1964730..1965599 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
NUG48_RS09730 (NUG48_09730) 1965616..1965954 + 339 WP_002911404.1 YebY family protein -
- 1966077..1966222 - 146 - - Antitoxin
- 1966113..1966215 + 103 - - Toxin
NUG48_RS09735 (NUG48_09735) 1966591..1966734 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
NUG48_RS09740 (NUG48_09740) 1966839..1967807 - 969 WP_014907334.1 VirK/YbjX family protein -
NUG48_RS09745 (NUG48_09745) 1967964..1968617 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
NUG48_RS09750 (NUG48_09750) 1968614..1968805 - 192 WP_257874023.1 YebW family protein -
NUG48_RS09755 (NUG48_09755) 1968903..1969142 - 240 WP_002911393.1 YebV family protein -
NUG48_RS09760 (NUG48_09760) 1969258..1970691 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253854 NZ_CP102552:1966113-1966215 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253854 NZ_CP102552:c1966222-1966077 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References