Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 2177417..2177906 Replicon chromosome
Accession NZ_CP102541
Organism Bifidobacterium longum subsp. infantis strain BB-02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NUU11_RS10200 Protein ID WP_229773994.1
Coordinates 2177417..2177644 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A4V2N072
Locus tag NUU11_RS10205 Protein ID WP_032744823.1
Coordinates 2177670..2177906 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUU11_RS10185 (NUU11_10185) 2174640..2175362 - 723 WP_060620046.1 hypothetical protein -
NUU11_RS10190 (NUU11_10190) 2175427..2176383 - 957 WP_212105731.1 A/G-specific adenine glycosylase -
NUU11_RS10195 (NUU11_10195) 2176404..2177066 + 663 WP_003828427.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
NUU11_RS10200 (NUU11_10200) 2177417..2177644 - 228 WP_229773994.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NUU11_RS10205 (NUU11_10205) 2177670..2177906 - 237 WP_032744823.1 ribbon-helix-helix domain-containing protein Antitoxin
NUU11_RS10210 (NUU11_10210) 2179213..2180538 - 1326 WP_234932960.1 MFS transporter -
NUU11_RS10215 (NUU11_10215) 2180566..2181753 - 1188 WP_174774172.1 carboxylate--amine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-72)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8653.22 Da        Isoelectric Point: 10.1818

>T253824 WP_229773994.1 NZ_CP102541:c2177644-2177417 [Bifidobacterium longum subsp. infantis]
MKKLDRNVAKRIIAKLREISQLEDPRSTGKALAGNLAGLWRYRVGDYRIVCDIEDEVLLILVIDVAHRSKVYKRC

Download         Length: 228 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8928.15 Da        Isoelectric Point: 4.2821

>AT253824 WP_032744823.1 NZ_CP102541:c2177906-2177670 [Bifidobacterium longum subsp. infantis]
MATVTAALRMPVELAARYDCLAKATGRTKTFYMNEALTESIDRFEYEYGIMKKVEDWRAGRLETVTLDELEESLGLED

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A4V2N072

References