Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 5132934..5133501 Replicon chromosome
Accession NZ_CP102512
Organism Streptomyces sp. CA-210063

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JIX56_RS22270 Protein ID WP_257542964.1
Coordinates 5132934..5133215 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JIX56_RS22275 Protein ID WP_257542965.1
Coordinates 5133220..5133501 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JIX56_RS22250 (JIX56_22250) 5128569..5129786 - 1218 WP_257542960.1 IS1380 family transposase -
JIX56_RS22255 (JIX56_22255) 5129908..5130228 - 321 WP_257542961.1 hypothetical protein -
JIX56_RS22260 (JIX56_22260) 5130921..5131118 + 198 WP_257542962.1 hypothetical protein -
JIX56_RS22265 (JIX56_22265) 5131338..5131685 - 348 WP_257542963.1 DUF1330 domain-containing protein -
JIX56_RS22270 (JIX56_22270) 5132934..5133215 - 282 WP_257542964.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JIX56_RS22275 (JIX56_22275) 5133220..5133501 - 282 WP_257542965.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JIX56_RS22280 (JIX56_22280) 5133749..5135836 - 2088 WP_257542966.1 RICIN domain-containing protein -
JIX56_RS22285 (JIX56_22285) 5136164..5137192 + 1029 WP_257542967.1 LacI family DNA-binding transcriptional regulator -
JIX56_RS22290 (JIX56_22290) 5137236..5137994 + 759 WP_257542968.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 5128569..5129786 1217


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10735.40 Da        Isoelectric Point: 10.2329

>T253804 WP_257542964.1 NZ_CP102512:c5133215-5132934 [Streptomyces sp. CA-210063]
MGYVTRFTPHAQRDMLKVPRPDALRILYRLTELQKAMDAGDTASFDLKALQGHSARWRLSIGDYRLVHTVEDGQLIVWVL
AVGNRRDIYRQVP

Download         Length: 282 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10446.55 Da        Isoelectric Point: 4.1952

>AT253804 WP_257542965.1 NZ_CP102512:c5133501-5133220 [Streptomyces sp. CA-210063]
MSDPVVESMAEVRSHLADVIDRARREETPTIITRRGKQEAVVIDIQEYQRLREIAENAEEAWLNQLADEAESEGTEGSVS
LEEMAALLRAHQG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References