Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/ElaA-DUF1778
Location 60..799 Replicon plasmid pCF10-C
Accession NZ_CP102503
Organism Citrobacter youngae strain CF10

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NUG39_RS25845 Protein ID WP_045337432.1
Coordinates 60..545 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag NUG39_RS25850 Protein ID WP_045334712.1
Coordinates 533..799 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG39_RS25845 (NUG39_25845) 60..545 - 486 WP_045337432.1 GNAT family N-acetyltransferase Toxin
NUG39_RS25850 (NUG39_25850) 533..799 - 267 WP_045334712.1 DUF1778 domain-containing protein Antitoxin
NUG39_RS25855 (NUG39_25855) 1453..2466 + 1014 WP_045337434.1 plasmid replication initiator RepA -
NUG39_RS25860 (NUG39_25860) 3346..4152 + 807 WP_045337436.1 DUF4225 domain-containing protein -
NUG39_RS25865 (NUG39_25865) 4127..4453 - 327 WP_045337438.1 hypothetical protein -
NUG39_RS25870 (NUG39_25870) 4585..5355 - 771 WP_045337440.1 TraX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..80740 80740


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-151)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17572.22 Da        Isoelectric Point: 9.5816

>T253800 WP_045337432.1 NZ_CP102503:c545-60 [Citrobacter youngae]
VGRVTAPEPLTSSHQLTEFVSGEAVLDDWLKQGGLKNQALGSARTFVVCKTGTKQVVGFYSLATGSVNHVEATGNIRRNM
PDPIPVIILARLAVDFSFRGQGLGADLLHDAVLRCYRVADNIGVRAIMVHALTEEAKSFYLHHGFKASKTQERTLFLKLP
Q

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10080.46 Da        Isoelectric Point: 4.3721

>AT253800 WP_045334712.1 NZ_CP102503:c799-533 [Citrobacter youngae]
MKSDIQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVSDDAAIDKLL
ARKPQWDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References