Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/ElaA-DUF1778 |
Location | 60..799 | Replicon | plasmid pCF10-C |
Accession | NZ_CP102503 | ||
Organism | Citrobacter youngae strain CF10 |
Toxin (Protein)
Gene name | tacT | Uniprot ID | - |
Locus tag | NUG39_RS25845 | Protein ID | WP_045337432.1 |
Coordinates | 60..545 (-) | Length | 162 a.a. |
Antitoxin (Protein)
Gene name | tacA | Uniprot ID | - |
Locus tag | NUG39_RS25850 | Protein ID | WP_045334712.1 |
Coordinates | 533..799 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NUG39_RS25845 (NUG39_25845) | 60..545 | - | 486 | WP_045337432.1 | GNAT family N-acetyltransferase | Toxin |
NUG39_RS25850 (NUG39_25850) | 533..799 | - | 267 | WP_045334712.1 | DUF1778 domain-containing protein | Antitoxin |
NUG39_RS25855 (NUG39_25855) | 1453..2466 | + | 1014 | WP_045337434.1 | plasmid replication initiator RepA | - |
NUG39_RS25860 (NUG39_25860) | 3346..4152 | + | 807 | WP_045337436.1 | DUF4225 domain-containing protein | - |
NUG39_RS25865 (NUG39_25865) | 4127..4453 | - | 327 | WP_045337438.1 | hypothetical protein | - |
NUG39_RS25870 (NUG39_25870) | 4585..5355 | - | 771 | WP_045337440.1 | TraX family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..80740 | 80740 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 17572.22 Da Isoelectric Point: 9.5816
>T253800 WP_045337432.1 NZ_CP102503:c545-60 [Citrobacter youngae]
VGRVTAPEPLTSSHQLTEFVSGEAVLDDWLKQGGLKNQALGSARTFVVCKTGTKQVVGFYSLATGSVNHVEATGNIRRNM
PDPIPVIILARLAVDFSFRGQGLGADLLHDAVLRCYRVADNIGVRAIMVHALTEEAKSFYLHHGFKASKTQERTLFLKLP
Q
VGRVTAPEPLTSSHQLTEFVSGEAVLDDWLKQGGLKNQALGSARTFVVCKTGTKQVVGFYSLATGSVNHVEATGNIRRNM
PDPIPVIILARLAVDFSFRGQGLGADLLHDAVLRCYRVADNIGVRAIMVHALTEEAKSFYLHHGFKASKTQERTLFLKLP
Q
Download Length: 486 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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