253788

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 4372239..4372962 Replicon chromosome
Accession NZ_CP102500
Organism Citrobacter youngae strain CF10

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NUG39_RS21045 Protein ID WP_257748387.1
Coordinates 4372239..4372559 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NUG39_RS21050 Protein ID WP_105607669.1
Coordinates 4372627..4372962 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG39_RS21015 (4368158) 4368158..4368520 + 363 WP_071667320.1 endoribonuclease SymE -
NUG39_RS21020 (4368757) 4368757..4369431 + 675 WP_257748384.1 hypothetical protein -
NUG39_RS21025 (4369433) 4369433..4369780 + 348 WP_257748385.1 hypothetical protein -
NUG39_RS21030 (4369783) 4369783..4370262 + 480 WP_199946147.1 type VI secretion system tube protein TssD -
NUG39_RS21035 (4370481) 4370481..4370807 - 327 WP_115601056.1 DUF1493 family protein -
NUG39_RS21040 (4371004) 4371004..4371876 + 873 WP_257748386.1 HNH endonuclease -
NUG39_RS21045 (4372239) 4372239..4372559 - 321 WP_257748387.1 toxin Toxin
NUG39_RS21050 (4372627) 4372627..4372962 - 336 WP_105607669.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NUG39_RS21055 (4372976) 4372976..4373455 - 480 WP_102217336.1 DNA repair protein RadC -
NUG39_RS21060 (4373467) 4373467..4373916 - 450 WP_257748388.1 antirestriction protein -
NUG39_RS21065 (4374013) 4374013..4374252 - 240 WP_097755449.1 DUF905 domain-containing protein -
NUG39_RS21070 (4374328) 4374328..4374795 - 468 WP_257748389.1 protein YfjT -
NUG39_RS21075 (4374819) 4374819..4375259 - 441 WP_148369041.1 hypothetical protein -
NUG39_RS21080 (4375259) 4375259..4375495 - 237 WP_001144029.1 protein YpjK -
NUG39_RS21085 (4375536) 4375536..4376237 - 702 WP_249642648.1 WYL domain-containing protein -
NUG39_RS21090 (4376454) 4376454..4377275 - 822 WP_257748390.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12074.86 Da        Isoelectric Point: 6.4799

>T253788 WP_257748387.1 NZ_CP102500:c4372559-4372239 [Citrobacter youngae]
MQISTVPATMPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPLHDDAAIKEHIEAGITLADAVNFLVERYELVRTDRKGF
TWQEQTPFVTAIDILRARRATGLMNK

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12594.36 Da        Isoelectric Point: 7.0262

>AT253788 WP_105607669.1 NZ_CP102500:c4372962-4372627 [Citrobacter youngae]
MYKDATPTWGLRRDITPCFGARLVQEGHRLHFLANRAGFTGSFSEVQTLQLNEAFPHFVAYLELMLLSCELNPRYAHCVT
LYRNGLTCEADTLGSHGHVYMAIYPSNQVKD

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References