Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3920657..3921363 Replicon chromosome
Accession NZ_CP102500
Organism Citrobacter youngae strain CF10

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag NUG39_RS18925 Protein ID WP_257748251.1
Coordinates 3920657..3921025 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NUG39_RS18930 Protein ID WP_257748253.1
Coordinates 3921046..3921363 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG39_RS18910 (3916311) 3916311..3917399 + 1089 WP_061067354.1 ABC transporter substrate-binding protein -
NUG39_RS18915 (3917476) 3917476..3919245 + 1770 WP_005133551.1 iron ABC transporter permease -
NUG39_RS18920 (3919238) 3919238..3920308 + 1071 WP_101742737.1 ABC transporter ATP-binding protein -
NUG39_RS18925 (3920657) 3920657..3921025 - 369 WP_257748251.1 toxin Toxin
NUG39_RS18930 (3921046) 3921046..3921363 - 318 WP_257748253.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NUG39_RS18935 (3921382) 3921382..3921603 - 222 WP_257748254.1 DUF987 domain-containing protein -
NUG39_RS18940 (3921612) 3921612..3922088 - 477 WP_257748255.1 RadC family protein -
NUG39_RS18945 (3922104) 3922104..3922562 - 459 WP_257748256.1 antirestriction protein -
NUG39_RS18950 (3922648) 3922648..3922884 - 237 WP_257748257.1 DUF905 domain-containing protein -
NUG39_RS18955 (3922962) 3922962..3923372 - 411 WP_257748258.1 hypothetical protein -
NUG39_RS18960 (3923439) 3923439..3923876 - 438 WP_047028252.1 hypothetical protein -
NUG39_RS18965 (3923918) 3923918..3924454 - 537 WP_257748259.1 DUF4339 domain-containing protein -
NUG39_RS18970 (3924480) 3924480..3925187 - 708 WP_257748260.1 DeoR family transcriptional regulator -
NUG39_RS18975 (3925396) 3925396..3926220 - 825 WP_257748261.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3904807..3952236 47429


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13775.00 Da        Isoelectric Point: 9.0360

>T253787 WP_257748251.1 NZ_CP102500:c3921025-3920657 [Citrobacter youngae]
MKNLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLMLSDTPFSDETVIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTTTDILQARKACGLMSRYSYREVSNIVLSRSRL

Download         Length: 369 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11897.55 Da        Isoelectric Point: 7.3496

>AT253787 WP_257748253.1 NZ_CP102500:c3921363-3921046 [Citrobacter youngae]
MSNITWGLQRNITPRLGARLVQEGNRLHYLADRASITGKFSEAECLKLDVAFPHFISQMESMLTTGEMNPRHAHYVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References