253779

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 905668..906322 Replicon chromosome
Accession NZ_CP102500
Organism Citrobacter youngae strain CF10

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NUG39_RS04430 Protein ID WP_048213165.1
Coordinates 905668..906075 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A6N6K0R3
Locus tag NUG39_RS04435 Protein ID WP_005123351.1
Coordinates 906056..906322 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG39_RS04410 (901569) 901569..903302 - 1734 WP_257748828.1 single-stranded-DNA-specific exonuclease RecJ -
NUG39_RS04415 (903308) 903308..904021 - 714 WP_101742745.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NUG39_RS04420 (904045) 904045..904941 - 897 WP_005123354.1 site-specific tyrosine recombinase XerD -
NUG39_RS04425 (905055) 905055..905576 + 522 WP_048213164.1 flavodoxin FldB -
NUG39_RS04430 (905668) 905668..906075 - 408 WP_048213165.1 protein YgfX Toxin
NUG39_RS04435 (906056) 906056..906322 - 267 WP_005123351.1 FAD assembly factor SdhE Antitoxin
NUG39_RS04440 (906578) 906578..907558 + 981 WP_048213166.1 tRNA-modifying protein YgfZ -
NUG39_RS04445 (907649) 907649..908308 - 660 WP_003026947.1 hemolysin III family protein -
NUG39_RS04450 (908472) 908472..908783 - 312 WP_257748831.1 N(4)-acetylcytidine aminohydrolase -
NUG39_RS04455 (908836) 908836..909564 + 729 WP_061068520.1 MurR/RpiR family transcriptional regulator -
NUG39_RS04460 (909685) 909685..911118 + 1434 WP_172743128.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15940.86 Da        Isoelectric Point: 10.9468

>T253779 WP_048213165.1 NZ_CP102500:c906075-905668 [Citrobacter youngae]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVCAPWMIKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQQVKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10642.16 Da        Isoelectric Point: 5.1700

>AT253779 WP_005123351.1 NZ_CP102500:c906322-906056 [Citrobacter youngae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6N6K0R3

References