Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 3326191..3327697 Replicon chromosome
Accession NZ_CP102486
Organism Dechloromonas sp. A34

Toxin (Protein)


Gene name HipA1 Uniprot ID -
Locus tag NQE15_RS16655 Protein ID WP_265942842.1
Coordinates 3326432..3327697 (+) Length 422 a.a.

Antitoxin (Protein)


Gene name HipB1 Uniprot ID -
Locus tag NQE15_RS16650 Protein ID WP_265942840.1
Coordinates 3326191..3326442 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQE15_RS16625 3322096..3323442 + 1347 WP_265942830.1 phenylacetate--CoA ligase -
NQE15_RS16630 3323445..3323996 + 552 WP_265942832.1 alpha/beta hydrolase -
NQE15_RS16635 3324192..3325166 - 975 WP_265942834.1 cysteine synthase A -
NQE15_RS16640 3325448..3325630 + 183 WP_265942836.1 hypothetical protein -
NQE15_RS16645 3325634..3325915 - 282 WP_265942838.1 DUF2325 domain-containing protein -
NQE15_RS16650 3326191..3326442 + 252 WP_265942840.1 helix-turn-helix transcriptional regulator Antitoxin
NQE15_RS16655 3326432..3327697 + 1266 WP_265942842.1 type II toxin-antitoxin system HipA family toxin Toxin
NQE15_RS16660 3327782..3328759 - 978 WP_265942844.1 ATP-binding cassette domain-containing protein -
NQE15_RS16665 3328771..3329559 - 789 WP_265942846.1 aliphatic sulfonate ABC transporter permease SsuC -
NQE15_RS16670 3329580..3329795 - 216 WP_265942848.1 molybdopterin-binding protein -
NQE15_RS16675 3329969..3330826 - 858 WP_265942849.1 amidohydrolase family protein -
NQE15_RS16680 3330895..3331914 - 1020 WP_265942851.1 sulfonate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(147-380)

Antitoxin

Transcription regulator, HipB-like

(9-65)


Sequences

Toxin        


Download         Length: 422 a.a.        Molecular weight: 46070.04 Da        Isoelectric Point: 7.9906

>T253734 WP_265942842.1 NZ_CP102486:3326432-3327697 [Dechloromonas sp. A34]
MTLELAVWLFAYAVGTLSLSEGRLAFQYRTDWLQRPDALALSASLPLQAEAFDDHQARPFFAGLLPEGRLRRLIAQQLHV
SGQNDFALLDSIGGECAGAITFLPPGQPLPAPAAEDAVRWLDDNEIVAMLDELPRRPMLAGKDGLRLSLAGAQDKLPVVF
DGQRLGLPQSGRPSTHILKPPIHGLADTVANEAFCLALAEAMKFPTARSQIGQVGNRCFLLVERYDRPPQPQEPASRLHQ
EDFCQALGVVPEMKYQNEGGPDLARCFDLLRRVTRPSAPQVLRLLDAVVFNALIGNHDAHAKNFSLLYSGRSPVLAPLYD
ILCTAAYPDLTPKMAMKIGSKYKFAEVQARHWDQFAEGAGLARAQSRKRVGELARALPAAARKLQAQAGRGFAGLPLIEQ
IVSLIEQRAALTLRRLQDNTG

Download         Length: 1266 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8427.72 Da        Isoelectric Point: 9.0051

>AT253734 WP_265942840.1 NZ_CP102486:3326191-3326442 [Dechloromonas sp. A34]
MAGIRSTQQLGDSLRAARKQLALTQAQLALAAGVGVRFIVDLEAGKPTLRLAQVLRVIDALGGELALNGLPVPSAGGGDS
HDA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References