Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1277471..1277994 Replicon chromosome
Accession NZ_CP102483
Organism Burkholderia contaminans strain DM32

Toxin (Protein)


Gene name relE Uniprot ID A0A2S8ISR8
Locus tag NTJ56_RS24040 Protein ID WP_034180530.1
Coordinates 1277471..1277737 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NTJ56_RS24045 Protein ID WP_089441963.1
Coordinates 1277734..1277994 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTJ56_RS24015 (NTJ56_24015) 1272655..1273893 - 1239 WP_226223756.1 diaminopimelate decarboxylase -
NTJ56_RS24020 (NTJ56_24020) 1274003..1274917 + 915 WP_226223755.1 LysR family transcriptional regulator -
NTJ56_RS24025 (NTJ56_24025) 1274986..1275585 + 600 WP_226223754.1 GNAT family protein -
NTJ56_RS24030 (NTJ56_24030) 1275702..1276280 - 579 WP_226223753.1 DUF4142 domain-containing protein -
NTJ56_RS24035 (NTJ56_24035) 1276675..1277298 - 624 WP_039360815.1 HAD hydrolase-like protein -
NTJ56_RS24040 (NTJ56_24040) 1277471..1277737 - 267 WP_034180530.1 Txe/YoeB family addiction module toxin Toxin
NTJ56_RS24045 (NTJ56_24045) 1277734..1277994 - 261 WP_089441963.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NTJ56_RS24050 (NTJ56_24050) 1278218..1278670 + 453 WP_226223751.1 GNAT family N-acetyltransferase -
NTJ56_RS24055 (NTJ56_24055) 1278728..1278946 + 219 WP_006480837.1 DUF1653 domain-containing protein -
NTJ56_RS24060 (NTJ56_24060) 1278998..1280212 - 1215 WP_226223749.1 crosslink repair DNA glycosylase YcaQ family protein -
NTJ56_RS24065 (NTJ56_24065) 1280596..1281984 - 1389 WP_226223747.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10478.81 Da        Isoelectric Point: 7.9861

>T253725 WP_034180530.1 NZ_CP102483:c1277737-1277471 [Burkholderia contaminans]
MSVRRVLVTSDAWDDYVYWQGQDRKTLKRINQLIREAQRTPFEGIGKPEPLKANLSGFWSRRIDDTNRLVYEADDLQISI
VSCRYHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9706.01 Da        Isoelectric Point: 6.7250

>AT253725 WP_089441963.1 NZ_CP102483:c1277994-1277734 [Burkholderia contaminans]
MRTIHFSDARGNLKTVIDQVVDDADVTLITRRDAPNAVIMSQDYYDSLMETVHLLRSPANVAHLERSIAQLRKGKAKERK
LAADDE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S8ISR8

Antitoxin

Source ID Structure

References