Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 86747..87330 Replicon chromosome
Accession NZ_CP102483
Organism Burkholderia contaminans strain DM32

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NTJ56_RS18625 Protein ID WP_226222489.1
Coordinates 86747..87127 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NTJ56_RS18630 Protein ID WP_089463371.1
Coordinates 87124..87330 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTJ56_RS18605 (NTJ56_18605) 83062..84141 - 1080 WP_226222491.1 homoserine dehydrogenase -
NTJ56_RS18610 (NTJ56_18610) 84292..84789 - 498 WP_226117924.1 Lrp/AsnC family transcriptional regulator -
NTJ56_RS18615 (NTJ56_18615) 84821..85501 - 681 WP_226117926.1 hypothetical protein -
NTJ56_RS18620 (NTJ56_18620) 85807..86643 + 837 WP_226222490.1 ion transporter -
NTJ56_RS18625 (NTJ56_18625) 86747..87127 - 381 WP_226222489.1 VapC toxin family PIN domain ribonuclease Toxin
NTJ56_RS18630 (NTJ56_18630) 87124..87330 - 207 WP_089463371.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NTJ56_RS18635 (NTJ56_18635) 87455..88123 - 669 WP_226222583.1 MarC family protein -
NTJ56_RS18640 (NTJ56_18640) 88383..89105 - 723 WP_226222486.1 arsenical resistance protein ArsH -
NTJ56_RS18645 (NTJ56_18645) 89102..90199 - 1098 WP_226222484.1 ACR3 family arsenite efflux transporter -
NTJ56_RS18650 (NTJ56_18650) 90264..90755 - 492 WP_226222482.1 arsenate reductase ArsC -
NTJ56_RS18655 (NTJ56_18655) 90778..91125 - 348 WP_226117934.1 metalloregulator ArsR/SmtB family transcription factor -
NTJ56_RS18660 (NTJ56_18660) 91228..92214 - 987 WP_226222480.1 serine protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13958.25 Da        Isoelectric Point: 6.4506

>T253724 WP_226222489.1 NZ_CP102483:c87127-86747 [Burkholderia contaminans]
MNVLIDTSVWVDHFRNRNQTLFGLLALDAVLMHPMVLGELACGTPPAPRLRTLSDLGLLQECNQASMREVMAFVERESLY
GMGYGLVDLTLLASTLITPGARFWTLDRRLAALADRFSVAFRSTSA

Download         Length: 381 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7657.80 Da        Isoelectric Point: 6.2811

>AT253724 WP_089463371.1 NZ_CP102483:c87330-87124 [Burkholderia contaminans]
MRTTVTIDDDLYTKALQMAEPGMDKADLFREAIKTFVRVQAAKRLAALGGTMSDMADIPRRRQEPESQ

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References