Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3739778..3740231 Replicon chromosome
Accession NZ_CP102482
Organism Burkholderia contaminans strain DM32

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NTJ56_RS17835 Protein ID WP_196486999.1
Coordinates 3739778..3740053 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NTJ56_RS17840 Protein ID WP_059890171.1
Coordinates 3740040..3740231 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTJ56_RS17815 (NTJ56_17815) 3737375..3737680 + 306 WP_059890164.1 hypothetical protein -
NTJ56_RS17820 (NTJ56_17820) 3737887..3738465 - 579 WP_059890166.1 ankyrin repeat domain-containing protein -
NTJ56_RS17825 (NTJ56_17825) 3738611..3738952 - 342 WP_059890167.1 hypothetical protein -
NTJ56_RS17830 (NTJ56_17830) 3739009..3739662 - 654 WP_059890169.1 ParA family protein -
NTJ56_RS17835 (NTJ56_17835) 3739778..3740053 - 276 WP_196486999.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NTJ56_RS17840 (NTJ56_17840) 3740040..3740231 - 192 WP_059890171.1 hypothetical protein Antitoxin
NTJ56_RS17845 (NTJ56_17845) 3740327..3740713 - 387 WP_059890173.1 hypothetical protein -
NTJ56_RS17850 (NTJ56_17850) 3740735..3741052 - 318 WP_059890174.1 hypothetical protein -
NTJ56_RS17855 (NTJ56_17855) 3741503..3741937 - 435 WP_059890178.1 ankyrin repeat domain-containing protein -
NTJ56_RS17860 (NTJ56_17860) 3742029..3742619 - 591 WP_059890179.1 hypothetical protein -
NTJ56_RS17865 (NTJ56_17865) 3742710..3743024 - 315 WP_059890181.1 hypothetical protein -
NTJ56_RS17870 (NTJ56_17870) 3743120..3743635 - 516 WP_059890183.1 ankyrin repeat domain-containing protein -
NTJ56_RS17875 (NTJ56_17875) 3743819..3744169 - 351 WP_059890184.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3706950..3762915 55965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10508.16 Da        Isoelectric Point: 8.0686

>T253723 WP_196486999.1 NZ_CP102482:c3740053-3739778 [Burkholderia contaminans]
MLPVEWRPRARFRLHKILSDIAELNVFAADDLANDIEQATSNLPAHPYLYRLGRVAGTREIVVHPNYIVIYRVCPAFIEV
VNVVHARQQYP

Download         Length: 276 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7040.83 Da        Isoelectric Point: 4.2550

>AT253723 WP_059890171.1 NZ_CP102482:c3740231-3740040 [Burkholderia contaminans]
MNAILSPIESEFTTAEEAEAYDRWLRAEVQASLDDPAPNIPHDEVMGDVRAMLAERKARNAAR

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References