253721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 3679281..3679786 Replicon chromosome
Accession NZ_CP102480
Organism Nisaea acidiphila strain MEBiC11861

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NUH88_RS17175 Protein ID WP_257767624.1
Coordinates 3679532..3679786 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag NUH88_RS17170 Protein ID WP_257767623.1
Coordinates 3679281..3679535 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUH88_RS17155 (NUH88_17155) 3674563..3676749 - 2187 WP_257767620.1 excinuclease ABC subunit UvrB -
NUH88_RS17160 (NUH88_17160) 3676986..3678638 + 1653 WP_257767621.1 anti-phage dCTP deaminase -
NUH88_RS17165 (NUH88_17165) 3678640..3679146 + 507 WP_257767622.1 hypothetical protein -
NUH88_RS17170 (NUH88_17170) 3679281..3679535 + 255 WP_257767623.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NUH88_RS17175 (NUH88_17175) 3679532..3679786 + 255 WP_257767624.1 Txe/YoeB family addiction module toxin Toxin
NUH88_RS17180 (NUH88_17180) 3679958..3680752 - 795 WP_257767625.1 SDR family NAD(P)-dependent oxidoreductase -
NUH88_RS17185 (NUH88_17185) 3680936..3681958 + 1023 WP_257767626.1 flagellar motor switch protein FliG -
NUH88_RS17190 (NUH88_17190) 3682051..3683025 + 975 WP_257767627.1 2OG-Fe(II) oxygenase family protein -
NUH88_RS17195 (NUH88_17195) 3683029..3683529 - 501 WP_257767628.1 DUF302 domain-containing protein -
NUH88_RS17200 (NUH88_17200) 3683627..3684166 - 540 WP_257767629.1 PAS domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3679281..3689678 10397


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10382.90 Da        Isoelectric Point: 9.9180

>T253721 WP_257767624.1 NZ_CP102480:3679532-3679786 [Nisaea acidiphila]
MKLVFHERAWEDYLHWQKTDRKLHQRLNALIRECTRTPFEGTGKPEPLRGPLSGWWSRRLTLEHRLVYRVHEDQLQIAQC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9410.47 Da        Isoelectric Point: 4.4290

>AT253721 WP_257767623.1 NZ_CP102480:3679281-3679535 [Nisaea acidiphila]
MRTKSYSDLRRNLAATLDSVTADHEPVIITRDRGKPAAVLMSLEDFASYEETRYLLRSPENADRLIEAVSALEAGAGREE
QLEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References