Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 3679281..3679786 Replicon chromosome
Accession NZ_CP102480
Organism Nisaea acidiphila strain MEBiC11861

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NUH88_RS17175 Protein ID WP_257767624.1
Coordinates 3679532..3679786 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag NUH88_RS17170 Protein ID WP_257767623.1
Coordinates 3679281..3679535 (+) Length 85 a.a.

Genomic Context

NUH88_RS17160NUH88_RS17165NUH88_RS17170NUH88_RS17175NUH88_RS17185NUH88_RS17190NUH88_RS17155NUH88_RS17180NUH88_RS17195NUH88_RS17200
Location: 3676986..3678638 (1653 bp)
Type: Others
Protein ID: WP_257767621.1
Location: 3678640..3679146 (507 bp)
Type: Others
Protein ID: WP_257767622.1
Location: 3679281..3679535 (255 bp)
Type: Antitoxin
Protein ID: WP_257767623.1
Location: 3679532..3679786 (255 bp)
Type: Toxin
Protein ID: WP_257767624.1
Location: 3680936..3681958 (1023 bp)
Type: Others
Protein ID: WP_257767626.1
Location: 3682051..3683025 (975 bp)
Type: Others
Protein ID: WP_257767627.1
Location: 3674563..3676749 (2187 bp)
Type: Others
Protein ID: WP_257767620.1
Location: 3679958..3680752 (795 bp)
Type: Others
Protein ID: WP_257767625.1
Location: 3683029..3683529 (501 bp)
Type: Others
Protein ID: WP_257767628.1
Location: 3683627..3684166 (540 bp)
Type: Others
Protein ID: WP_257767629.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NUH88_RS17155 (NUH88_17155)3674563..3676749-2187WP_257767620.1excinuclease ABC subunit UvrB-
NUH88_RS17160 (NUH88_17160)3676986..3678638+1653WP_257767621.1anti-phage dCTP deaminase-
NUH88_RS17165 (NUH88_17165)3678640..3679146+507WP_257767622.1hypothetical protein-
NUH88_RS17170 (NUH88_17170)3679281..3679535+255WP_257767623.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
NUH88_RS17175 (NUH88_17175)3679532..3679786+255WP_257767624.1Txe/YoeB family addiction module toxinToxin
NUH88_RS17180 (NUH88_17180)3679958..3680752-795WP_257767625.1SDR family NAD(P)-dependent oxidoreductase-
NUH88_RS17185 (NUH88_17185)3680936..3681958+1023WP_257767626.1flagellar motor switch protein FliG-
NUH88_RS17190 (NUH88_17190)3682051..3683025+975WP_257767627.12OG-Fe(II) oxygenase family protein-
NUH88_RS17195 (NUH88_17195)3683029..3683529-501WP_257767628.1DUF302 domain-containing protein-
NUH88_RS17200 (NUH88_17200)3683627..3684166-540WP_257767629.1PAS domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--3679281..368967810397


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10382.90 Da        Isoelectric Point: 9.9180

>T253721 WP_257767624.1 NZ_CP102480:3679532-3679786 [Nisaea acidiphila]
MKLVFHERAWEDYLHWQKTDRKLHQRLNALIRECTRTPFEGTGKPEPLRGPLSGWWSRRLTLEHRLVYRVHEDQLQIAQC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9410.47 Da        Isoelectric Point: 4.4290

>AT253721 WP_257767623.1 NZ_CP102480:3679281-3679535 [Nisaea acidiphila]
MRTKSYSDLRRNLAATLDSVTADHEPVIITRDRGKPAAVLMSLEDFASYEETRYLLRSPENADRLIEAVSALEAGAGREE
QLEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References