Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 870704..871361 Replicon chromosome
Accession NZ_CP102479
Organism Klebsiella aerogenes strain TS2020

Toxin (Protein)


Gene name cptA Uniprot ID A0A0H3FM52
Locus tag NUT96_RS04225 Protein ID WP_015369792.1
Coordinates 870951..871361 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NUT96_RS04220 Protein ID WP_032709107.1
Coordinates 870704..870970 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUT96_RS04195 (865931) 865931..867364 - 1434 WP_032712496.1 6-phospho-beta-glucosidase BglA -
NUT96_RS04200 (867484) 867484..868212 - 729 WP_015369788.1 MurR/RpiR family transcriptional regulator -
NUT96_RS04205 (868263) 868263..868574 + 312 WP_058649411.1 N(4)-acetylcytidine aminohydrolase -
NUT96_RS04210 (868739) 868739..869398 + 660 WP_008806429.1 hemolysin III family protein -
NUT96_RS04215 (869497) 869497..870480 - 984 WP_032709108.1 tRNA-modifying protein YgfZ -
NUT96_RS04220 (870704) 870704..870970 + 267 WP_032709107.1 FAD assembly factor SdhE Antitoxin
NUT96_RS04225 (870951) 870951..871361 + 411 WP_015369792.1 protein YgfX Toxin
NUT96_RS04230 (871369) 871369..871890 - 522 WP_015369793.1 flavodoxin FldB -
NUT96_RS04235 (871991) 871991..872887 + 897 WP_015703420.1 site-specific tyrosine recombinase XerD -
NUT96_RS04240 (872910) 872910..873623 + 714 WP_015369795.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NUT96_RS04245 (873629) 873629..875362 + 1734 WP_015369796.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15887.69 Da        Isoelectric Point: 10.0200

>T253711 WP_015369792.1 NZ_CP102479:870951-871361 [Klebsiella aerogenes]
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLMPWPLSYTPIWLLLLSLVVFDCVRSQRRIHACQGEIKLLIDSRLRWQKT
EWDIVGTPWVISSGMLLRLKHAETGRSQHLWVAADSMDAGEWRDLRRLVLQKPAHD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10609.12 Da        Isoelectric Point: 5.6963

>AT253711 WP_032709107.1 NZ_CP102479:870704-870970 [Klebsiella aerogenes]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGKPADTQLQRMINLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3FM52

Antitoxin

Source ID Structure

References