Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1956150..1956775 Replicon chromosome
Accession NZ_CP102473
Organism Burkholderia multivorans strain NML140411

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NUJ31_RS24610 Protein ID WP_105801348.1
Coordinates 1956320..1956775 (+) Length 152 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NUJ31_RS24605 Protein ID WP_176045645.1
Coordinates 1956150..1956323 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUJ31_RS24580 (NUJ31_24580) 1951232..1951375 - 144 WP_006409932.1 hypothetical protein -
NUJ31_RS24585 (NUJ31_24585) 1951964..1952167 + 204 WP_006403067.1 hypothetical protein -
NUJ31_RS24590 (NUJ31_24590) 1952181..1952864 - 684 WP_006396647.1 Fe2+-dependent dioxygenase -
NUJ31_RS24595 (NUJ31_24595) 1952861..1953616 - 756 WP_006403069.1 tetratricopeptide repeat protein -
NUJ31_RS24600 (NUJ31_24600) 1953620..1955866 - 2247 WP_006403070.1 TonB-dependent siderophore receptor -
NUJ31_RS24605 (NUJ31_24605) 1956150..1956323 + 174 WP_176045645.1 plasmid stability protein Antitoxin
NUJ31_RS24610 (NUJ31_24610) 1956320..1956775 + 456 WP_105801348.1 type II toxin-antitoxin system VapC family toxin Toxin
NUJ31_RS24615 (NUJ31_24615) 1956872..1958167 - 1296 WP_035487510.1 aspartate carbamoyltransferase -
NUJ31_RS24620 (NUJ31_24620) 1958400..1958534 + 135 WP_006396654.1 entericidin A/B family lipoprotein -
NUJ31_RS24625 (NUJ31_24625) 1958628..1959203 - 576 WP_105801347.1 permease -
NUJ31_RS24630 (NUJ31_24630) 1959406..1960356 - 951 WP_105801378.1 DMT family transporter -
NUJ31_RS24635 (NUJ31_24635) 1960905..1961699 - 795 WP_105848189.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 152 a.a.        Molecular weight: 16110.43 Da        Isoelectric Point: 6.4765

>T253701 WP_105801348.1 NZ_CP102473:1956320-1956775 [Burkholderia multivorans]
MILVDTNVISEPLRREPSAAVIEWLDAQNVETLFLAAISLAEMRFGVAALPEGRGRDWLAQSIEHRVVPVFRGRILPFDD
AASKAYARIRAHARAGGNAIAPADGYIAATAEANGLIVATRDVAPFEAAGLRVIDPWASQGAPVRQGIASK

Download         Length: 456 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6220.96 Da        Isoelectric Point: 4.3455

>AT253701 WP_176045645.1 NZ_CP102473:1956150-1956323 [Burkholderia multivorans]
MHGRSTEAEVRDILEQAVLSEGRVKLGTLLAEIGREAGGVDLDIQRDKTPTDPISFE

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References