Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 4060113..4060699 | Replicon | chromosome |
Accession | NC_015656 | ||
Organism | Frankia symbiont of Datisca glomerata |
Toxin (Protein)
Gene name | relE | Uniprot ID | F8B1H8 |
Locus tag | FSYMDG_RS16970 | Protein ID | WP_013874619.1 |
Coordinates | 4060113..4060403 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | F8B1H9 |
Locus tag | FSYMDG_RS16975 | Protein ID | WP_013874620.1 |
Coordinates | 4060400..4060699 (-) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FSYMDG_RS16935 | 4055240..4055440 | - | 201 | WP_043603892.1 | hypothetical protein | - |
FSYMDG_RS16940 | 4055437..4056651 | - | 1215 | WP_043606884.1 | acyl-CoA dehydrogenase | - |
FSYMDG_RS16945 | 4056919..4057938 | + | 1020 | WP_083828326.1 | formyltetrahydrofolate deformylase | - |
FSYMDG_RS16950 | 4057908..4058576 | - | 669 | WP_013874615.1 | phosphatase PAP2 family protein | - |
FSYMDG_RS16955 | 4059088..4059366 | + | 279 | WP_131772750.1 | Arc family DNA-binding protein | - |
FSYMDG_RS16960 | 4059363..4059704 | + | 342 | WP_013874617.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
FSYMDG_RS16965 | 4059830..4060018 | - | 189 | WP_013874618.1 | NUDIX hydrolase | - |
FSYMDG_RS16970 | 4060113..4060403 | - | 291 | WP_013874619.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FSYMDG_RS16975 | 4060400..4060699 | - | 300 | WP_013874620.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
FSYMDG_RS16980 | 4060944..4062031 | - | 1088 | Protein_3345 | IS630 family transposase | - |
FSYMDG_RS16985 | 4062006..4063823 | + | 1818 | WP_085948566.1 | protein kinase | - |
FSYMDG_RS16990 | 4063945..4064859 | + | 915 | WP_131772754.1 | MurR/RpiR family transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 4060944..4061156 | 212 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10830.23 Da Isoelectric Point: 9.5857
>T25370 WP_013874619.1 NC_015656:c4060403-4060113 [Candidatus Frankia datiscae]
VTGTGEQPFELRITGPAARALASRLPEKIAAAVHEFVTTTLLDNPHRLGRRLLLPPYEGTWSARRGSYRVLYEIDEDNRI
VTVTAVEHRSDAYRSR
VTGTGEQPFELRITGPAARALASRLPEKIAAAVHEFVTTTLLDNPHRLGRRLLLPPYEGTWSARRGSYRVLYEIDEDNRI
VTVTAVEHRSDAYRSR
Download Length: 291 bp
>T25370 NC_015656:c4060403-4060113 [Candidatus Frankia datiscae]
GTGACCGGAACTGGCGAGCAGCCGTTTGAACTTCGGATCACTGGTCCTGCGGCGCGTGCTCTCGCCAGCCGGTTGCCCGA
GAAGATCGCGGCTGCCGTCCACGAGTTCGTCACGACCACACTCCTGGACAATCCTCACCGGCTTGGCAGACGCCTCCTGC
TTCCACCGTACGAGGGCACCTGGTCCGCTCGTCGCGGCAGTTACCGGGTGTTGTATGAAATCGACGAGGACAACCGCATT
GTTACCGTGACCGCCGTCGAACATCGCTCCGACGCGTACCGCTCCCGCTGA
GTGACCGGAACTGGCGAGCAGCCGTTTGAACTTCGGATCACTGGTCCTGCGGCGCGTGCTCTCGCCAGCCGGTTGCCCGA
GAAGATCGCGGCTGCCGTCCACGAGTTCGTCACGACCACACTCCTGGACAATCCTCACCGGCTTGGCAGACGCCTCCTGC
TTCCACCGTACGAGGGCACCTGGTCCGCTCGTCGCGGCAGTTACCGGGTGTTGTATGAAATCGACGAGGACAACCGCATT
GTTACCGTGACCGCCGTCGAACATCGCTCCGACGCGTACCGCTCCCGCTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 11029.42 Da Isoelectric Point: 4.9737
>AT25370 WP_013874620.1 NC_015656:c4060699-4060400 [Candidatus Frankia datiscae]
MTVMPFTEARNRLSELIDEVGRTHERVEITRHGHAVAVLISPDDLAALEEALDVLASREAMRQLAESRDARESGDVLDAE
ELAALMAKRARRAESPHTR
MTVMPFTEARNRLSELIDEVGRTHERVEITRHGHAVAVLISPDDLAALEEALDVLASREAMRQLAESRDARESGDVLDAE
ELAALMAKRARRAESPHTR
Download Length: 300 bp
>AT25370 NC_015656:c4060699-4060400 [Candidatus Frankia datiscae]
ATGACTGTCATGCCGTTCACCGAGGCGCGCAACCGGCTGTCGGAGCTCATTGACGAGGTGGGGCGGACTCATGAGCGAGT
GGAGATCACCCGTCACGGGCATGCGGTGGCGGTCCTGATCTCTCCCGATGACCTGGCGGCGCTGGAGGAGGCGCTGGATG
TGTTGGCGAGTCGGGAGGCGATGCGGCAGCTTGCGGAATCCCGGGACGCCCGCGAGTCCGGCGACGTGCTCGATGCCGAG
GAGCTCGCCGCGCTCATGGCGAAACGGGCGCGCCGCGCCGAGTCGCCCCACACACGGTGA
ATGACTGTCATGCCGTTCACCGAGGCGCGCAACCGGCTGTCGGAGCTCATTGACGAGGTGGGGCGGACTCATGAGCGAGT
GGAGATCACCCGTCACGGGCATGCGGTGGCGGTCCTGATCTCTCCCGATGACCTGGCGGCGCTGGAGGAGGCGCTGGATG
TGTTGGCGAGTCGGGAGGCGATGCGGCAGCTTGCGGAATCCCGGGACGCCCGCGAGTCCGGCGACGTGCTCGATGCCGAG
GAGCTCGCCGCGCTCATGGCGAAACGGGCGCGCCGCGCCGAGTCGCCCCACACACGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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