Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 885785..886380 Replicon chromosome
Accession NZ_CP102464
Organism Burkholderia contaminans strain NML151013

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag NUJ29_RS36090 Protein ID WP_105817739.1
Coordinates 885785..886135 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID A0A0G3Z282
Locus tag NUJ29_RS36095 Protein ID WP_039362633.1
Coordinates 886129..886380 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUJ29_RS36080 (NUJ29_36080) 882622..884094 + 1473 WP_105817741.1 efflux RND transporter periplasmic adaptor subunit -
NUJ29_RS36085 (NUJ29_36085) 884126..885661 + 1536 WP_105817740.1 efflux transporter outer membrane subunit -
NUJ29_RS36090 (NUJ29_36090) 885785..886135 - 351 WP_105817739.1 type II toxin-antitoxin system ChpB family toxin Toxin
NUJ29_RS36095 (NUJ29_36095) 886129..886380 - 252 WP_039362633.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NUJ29_RS36100 (NUJ29_36100) 886548..886709 - 162 Protein_765 tyrosine-type recombinase/integrase -
NUJ29_RS36105 (NUJ29_36105) 886747..887178 + 432 Protein_766 hypothetical protein -
NUJ29_RS36110 (NUJ29_36110) 887366..889186 + 1821 WP_105817738.1 asparagine synthase (glutamine-hydrolyzing) -
NUJ29_RS36115 (NUJ29_36115) 889421..890881 - 1461 WP_105817737.1 heavy metal sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12373.27 Da        Isoelectric Point: 10.0752

>T253694 WP_105817739.1 NZ_CP102464:c886135-885785 [Burkholderia contaminans]
MVRRVKFERGDIVRVSLNPTVGKEQQGDFRPALVLSPAAFNALGVALVAPIAQGGEFARYAGFAVPLSGSGTETQGVALV
NMVRTLDLQARGARKVERAPSEVIEDALARLQTILE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8948.19 Da        Isoelectric Point: 4.7204

>AT253694 WP_039362633.1 NZ_CP102464:c886380-886129 [Burkholderia contaminans]
MELKIQKWGNSAAVRLPAVLLEQIDASVGSSLNADVRPDGVLLSPARRKYSLDELIAQCDPKAPEPADLAAWGESKPVGH
EAW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G3Z282

References