Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2002481..2002626 Replicon chromosome
Accession NZ_CP102438
Organism Klebsiella pneumoniae strain hvKP248

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2002517..2002619 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2002481..2002626 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUJ53_RS09740 1997611..1999671 + 2061 WP_004151449.1 oligopeptidase B -
NUJ53_RS09745 1999675..2000334 - 660 WP_002911407.1 exodeoxyribonuclease X -
NUJ53_RS09750 2000413..2000643 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NUJ53_RS09755 2000756..2001130 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NUJ53_RS09760 2001134..2002003 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
NUJ53_RS09765 2002020..2002358 + 339 WP_002911404.1 YebY family protein -
- 2002481..2002626 - 146 - - Antitoxin
- 2002517..2002619 + 103 - - Toxin
NUJ53_RS09770 2002994..2003137 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NUJ53_RS09775 2003242..2004210 - 969 WP_004151446.1 VirK/YbjX family protein -
NUJ53_RS09780 2004367..2005020 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
NUJ53_RS09785 2005017..2005208 - 192 WP_002911395.1 YebW family protein -
NUJ53_RS09790 2005306..2005545 - 240 WP_002911393.1 YebV family protein -
NUJ53_RS09795 2005661..2007094 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253658 NZ_CP102438:2002517-2002619 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253658 NZ_CP102438:c2002626-2002481 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References