Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 1033453..1034129 Replicon chromosome
Accession NC_015656
Organism Frankia symbiont of Datisca glomerata

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FSYMDG_RS04325 Protein ID WP_013872369.1
Coordinates 1033453..1033851 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FSYMDG_RS04330 Protein ID WP_202797673.1
Coordinates 1033848..1034129 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSYMDG_RS04310 1028834..1030324 + 1491 WP_013872366.1 TerD family protein -
FSYMDG_RS04315 1030629..1031828 - 1200 WP_013872367.1 acyl-CoA dehydrogenase family protein -
FSYMDG_RS04320 1032210..1033328 + 1119 WP_013872368.1 glycoside hydrolase family 6 protein -
FSYMDG_RS04325 1033453..1033851 - 399 WP_013872369.1 type II toxin-antitoxin system VapC family toxin Toxin
FSYMDG_RS04330 1033848..1034129 - 282 WP_202797673.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FSYMDG_RS04335 1034741..1036147 + 1407 WP_013872371.1 magnesium transporter -
FSYMDG_RS04340 1036147..1036788 + 642 WP_013872372.1 DUF1003 domain-containing protein -
FSYMDG_RS04345 1036931..1037230 - 300 WP_131772148.1 chorismate mutase -
FSYMDG_RS04350 1037619..1038464 + 846 WP_013872374.1 PD-(D/E)XK nuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-50)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14291.51 Da        Isoelectric Point: 6.7175

>T25365 WP_013872369.1 NC_015656:c1033851-1033453 [Candidatus Frankia datiscae]
MIYLDSCALVKLVVTEAETSALRAFLSAHAGYPQVTSLLARTEVVRAVRRATADDADLYKAAVTMLNRLDHIILDRPILD
DAGAVADPLVRTLDAIHLAAARRLGDSLTAFVTYDRRLATAALDFGFPVRAP

Download         Length: 399 bp

>T25365 NC_015656:c1033851-1033453 [Candidatus Frankia datiscae]
TTGATCTACCTGGACTCGTGCGCGCTGGTGAAACTGGTCGTCACCGAGGCCGAGACATCCGCGCTGCGCGCCTTCCTCAG
CGCGCACGCCGGGTATCCCCAGGTGACCTCCCTACTCGCCCGCACCGAGGTCGTCCGAGCGGTACGGCGCGCCACCGCGG
ACGACGCCGACCTGTATAAGGCTGCGGTGACCATGCTCAACCGCCTCGACCACATCATCCTGGACCGGCCCATCCTGGAC
GACGCCGGGGCGGTCGCCGACCCTCTGGTGCGCACCCTCGACGCGATCCATCTGGCCGCCGCGCGGCGGCTCGGCGACAG
CCTGACGGCGTTCGTCACCTACGACCGCCGCCTGGCCACCGCAGCCCTCGACTTCGGCTTCCCCGTCCGCGCCCCCTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10319.68 Da        Isoelectric Point: 4.5822

>AT25365 WP_202797673.1 NC_015656:c1034129-1033848 [Candidatus Frankia datiscae]
MMERIGVRELQHNASRILDRVKTGETIEITERGRLIAVLTPPSDLHQARARLIDEGVLQPGEGGLAEWEPGPPRTDGPAL
SEVLLDMRAEDDR

Download         Length: 282 bp

>AT25365 NC_015656:c1034129-1033848 [Candidatus Frankia datiscae]
ATGATGGAACGGATCGGCGTACGGGAGCTCCAGCACAACGCGTCCAGGATCCTCGATCGGGTCAAGACCGGCGAGACCAT
CGAGATCACCGAACGCGGCCGCCTTATCGCCGTCCTCACCCCACCCAGCGACCTCCACCAGGCACGGGCACGGCTGATCG
ACGAAGGAGTGCTCCAGCCCGGCGAGGGCGGTCTCGCCGAATGGGAACCCGGGCCCCCACGCACGGACGGGCCAGCGCTG
TCGGAGGTACTCCTCGACATGCGCGCCGAGGACGATCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References