Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2820694..2820839 Replicon chromosome
Accession NZ_CP102435
Organism Klebsiella pneumoniae strain K194

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2820701..2820803 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2820694..2820839 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NR799_RS13955 (NR799_13955) 2816226..2817659 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NR799_RS13960 (NR799_13960) 2817775..2818014 + 240 WP_002911393.1 YebV family protein -
NR799_RS13965 (NR799_13965) 2818112..2818303 + 192 WP_002911395.1 YebW family protein -
NR799_RS13970 (NR799_13970) 2818300..2818953 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
NR799_RS13975 (NR799_13975) 2819110..2820078 + 969 WP_004151446.1 VirK/YbjX family protein -
NR799_RS13980 (NR799_13980) 2820183..2820326 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2820694..2820839 + 146 - - Antitoxin
- 2820701..2820803 - 103 - - Toxin
NR799_RS13985 (NR799_13985) 2820962..2821300 - 339 WP_002911404.1 YebY family protein -
NR799_RS13990 (NR799_13990) 2821317..2822186 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NR799_RS13995 (NR799_13995) 2822190..2822564 - 375 WP_004151448.1 CopC domain-containing protein YobA -
NR799_RS14000 (NR799_14000) 2822677..2822907 + 231 WP_002911406.1 DNA polymerase III subunit theta -
NR799_RS14005 (NR799_14005) 2822986..2823645 + 660 WP_002911407.1 exodeoxyribonuclease X -
NR799_RS14010 (NR799_14010) 2823649..2825709 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253634 NZ_CP102435:c2820803-2820701 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253634 NZ_CP102435:2820694-2820839 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References