Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 34985..35583 Replicon plasmid unnamed2
Accession NZ_CP102430
Organism Pseudomonas psychrotolerans strain YY7

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NRG74_RS24050 Protein ID WP_257706796.1
Coordinates 34985..35287 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A178LES3
Locus tag NRG74_RS24055 Protein ID WP_064308223.1
Coordinates 35284..35583 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRG74_RS24010 (NRG74_24010) 30016..30219 - 204 WP_257706790.1 hypothetical protein -
NRG74_RS24015 (NRG74_24015) 30229..30441 - 213 WP_074585490.1 hypothetical protein -
NRG74_RS24020 (NRG74_24020) 30525..32207 - 1683 WP_257706791.1 DNA cytosine methyltransferase -
NRG74_RS24025 (NRG74_24025) 32259..32501 - 243 WP_257706792.1 hypothetical protein -
NRG74_RS24030 (NRG74_24030) 32644..33735 - 1092 WP_257706793.1 hypothetical protein -
NRG74_RS24035 (NRG74_24035) 33796..34014 - 219 WP_257706794.1 hypothetical protein -
NRG74_RS24040 (NRG74_24040) 34069..34389 - 321 WP_257706807.1 theronine dehydrogenase -
NRG74_RS24045 (NRG74_24045) 34419..34787 - 369 WP_257706795.1 hypothetical protein -
NRG74_RS24050 (NRG74_24050) 34985..35287 + 303 WP_257706796.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NRG74_RS24055 (NRG74_24055) 35284..35583 + 300 WP_064308223.1 putative addiction module antidote protein Antitoxin
NRG74_RS24060 (NRG74_24060) 36512..37039 - 528 WP_257706797.1 hypothetical protein -
NRG74_RS24065 (NRG74_24065) 37090..37572 - 483 WP_257706798.1 helix-turn-helix domain-containing protein -
NRG74_RS24070 (NRG74_24070) 38063..38491 + 429 WP_257706799.1 S24 family peptidase -
NRG74_RS24075 (NRG74_24075) 38481..39767 + 1287 WP_257706800.1 Y-family DNA polymerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid aph(6)-Id / aph(3'')-Ib - 1..98312 98312


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11194.80 Da        Isoelectric Point: 10.4673

>T253626 WP_257706796.1 NZ_CP102430:34985-35287 [Pseudomonas psychrotolerans]
MKTIKQTATFRNWERKLKDKQAKAIIAARVFRVANGLLGDVQPVGQGISELRIHHGPGYRVYFQQRGNQLVLLLCGGDKS
SQARDIETAKALASQWSDDE

Download         Length: 303 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10615.11 Da        Isoelectric Point: 4.7914

>AT253626 WP_064308223.1 NZ_CP102430:35284-35583 [Pseudomonas psychrotolerans]
MKEKIFDYDPADALTDPASIAVFLEDAFETGDAAYIAKALGVVARAKGMGEIAKESGLSRENLYRSFSENGNPTLKTMLA
VMQAVGLDLTARVHITPAH

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A178LES3

References