253605

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012810..2012955 Replicon chromosome
Accession NZ_CP102390
Organism Klebsiella pneumoniae strain K64

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012846..2012948 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012810..2012955 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRF21_RS09890 (NRF21_09890) 2007940..2010000 + 2061 WP_004151449.1 oligopeptidase B -
NRF21_RS09895 (NRF21_09895) 2010004..2010663 - 660 WP_002911407.1 exodeoxyribonuclease X -
NRF21_RS09900 (NRF21_09900) 2010742..2010972 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NRF21_RS09905 (NRF21_09905) 2011085..2011459 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NRF21_RS09910 (NRF21_09910) 2011463..2012332 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NRF21_RS09915 (NRF21_09915) 2012349..2012687 + 339 WP_002911404.1 YebY family protein -
- 2012810..2012955 - 146 - - Antitoxin
- 2012846..2012948 + 103 - - Toxin
NRF21_RS09920 (NRF21_09920) 2013323..2013466 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NRF21_RS09925 (NRF21_09925) 2013571..2014539 - 969 WP_004151446.1 VirK/YbjX family protein -
NRF21_RS09930 (NRF21_09930) 2014696..2015349 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NRF21_RS09935 (NRF21_09935) 2015346..2015537 - 192 WP_002911395.1 YebW family protein -
NRF21_RS09940 (NRF21_09940) 2015635..2015874 - 240 WP_002911393.1 YebV family protein -
NRF21_RS09945 (NRF21_09945) 2015990..2017423 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253605 NZ_CP102390:2012846-2012948 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253605 NZ_CP102390:c2012955-2012810 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References