Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 137917..138476 Replicon plasmid pDB-2
Accession NZ_CP102386
Organism Sphingopyxis sp. DBS4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NP825_RS22345 Protein ID WP_089220675.1
Coordinates 138183..138476 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID T0J1T8
Locus tag NP825_RS22340 Protein ID WP_020819389.1
Coordinates 137917..138186 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP825_RS22335 134103..137552 + 3450 WP_089220674.1 YhaN family protein -
NP825_RS22340 137917..138186 + 270 WP_020819389.1 ribbon-helix-helix domain-containing protein Antitoxin
NP825_RS22345 138183..138476 + 294 WP_089220675.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NP825_RS22350 138516..139127 - 612 WP_089220676.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
NP825_RS22355 139124..139972 - 849 WP_257551734.1 toprim domain-containing protein -
NP825_RS22360 140144..140326 + 183 WP_020819384.1 hypothetical protein -
NP825_RS22365 140645..141730 + 1086 WP_257551735.1 AAA family ATPase -
NP825_RS22370 141727..142797 + 1071 WP_257551736.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..227036 227036


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11387.05 Da        Isoelectric Point: 7.3579

>T253599 WP_089220675.1 NZ_CP102386:138183-138476 [Sphingopyxis sp. DBS4]
MKIQWTSKASSDLVRLHEHLGPVAPEAAARVVQQLAHAPDRLLDYPRIGEKLEAYEPREIRRIIVGNYEMRYEIAAGTIF
MLRLWHCRENRNFESEQ

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9829.20 Da        Isoelectric Point: 5.1312

>AT253599 WP_020819389.1 NZ_CP102386:137917-138186 [Sphingopyxis sp. DBS4]
MATETKVLTAHVPLGLAEKVEAMASRLERSRGWVVKQALAAWVDQEEERHRMTLEALEDVDAGRVIDHQAITAWADSLGT
DKPLPSPVK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2T4HNW7

References