Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 5517953..5518649 Replicon chromosome
Accession NC_015635
Organism Microlunatus phosphovorus NM-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MLP_RS24995 Protein ID WP_172641634.1
Coordinates 5517953..5518354 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MLP_RS25000 Protein ID WP_041790612.1
Coordinates 5518419..5518649 (-) Length 77 a.a.

Genomic Context

MLP_RS24985MLP_RS24990MLP_RS25005MLP_RS27700MLP_RS24995MLP_RS25000MLP_RS25010MLP_RS26885
Location: 5515945..5516748 (804 bp)
Type: Others
Protein ID: WP_013866011.1
Location: 5516745..5517824 (1080 bp)
Type: Others
Protein ID: WP_013866012.1
Location: 5518771..5519010 (240 bp)
Type: Others
Protein ID: WP_013866015.1
Location: 5519230..5519592 (363 bp)
Type: Others
Protein ID: WP_156821295.1
Location: 5517953..5518354 (402 bp)
Type: Toxin
Protein ID: WP_172641634.1
Location: 5518419..5518649 (231 bp)
Type: Antitoxin
Protein ID: WP_041790612.1
Location: 5519552..5520160 (609 bp)
Type: Others
Protein ID: WP_013866017.1
Location: 5521038..5522933 (1896 bp)
Type: Others
Protein ID: WP_013866018.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MLP_RS249855515945..5516748+804WP_013866011.1hypothetical protein-
MLP_RS249905516745..5517824+1080WP_013866012.1hypothetical protein-
MLP_RS249955517953..5518354-402WP_172641634.1VapC toxin family PIN domain ribonucleaseToxin
MLP_RS250005518419..5518649-231WP_041790612.1hypothetical proteinAntitoxin
MLP_RS250055518771..5519010+240WP_013866015.1DUF433 domain-containing protein-
MLP_RS277005519230..5519592+363WP_156821295.1hypothetical protein-
MLP_RS250105519552..5520160-609WP_013866017.1alpha/beta hydrolase fold domain-containing protein-
MLP_RS268855521038..5522933-1896WP_013866018.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14583.72 Da        Isoelectric Point: 6.8431

>T25359 WP_172641634.1 NC_015635:c5518354-5517953 [Microlunatus phosphovorus NM-1]
VNLLVALLHPAHVHHLQAQAWFTSVERFATTPITESGFIRMALNPAVAGQVTSLDDAMSSLNSVRADKRVEYVADDTSLA
LPTIDLVGLVGFRQVTDFHLVNLAACHSARLVTFDRKLAPTLAPEDRRFVHSL

Download         Length: 402 bp

>T25359 NC_015635:c5518354-5517953 [Microlunatus phosphovorus NM-1]
GTGAACTTGCTTGTCGCGCTGTTGCATCCGGCTCACGTCCATCACCTCCAAGCGCAGGCATGGTTCACCTCGGTTGAGCG
GTTTGCCACCACGCCGATCACCGAGTCCGGGTTCATCCGGATGGCACTCAACCCCGCAGTCGCCGGCCAGGTCACCTCCC
TTGATGACGCCATGTCCTCGCTGAACTCCGTACGAGCCGACAAGCGAGTGGAGTACGTTGCCGATGACACCTCGCTCGCC
CTACCGACAATCGATCTCGTCGGACTCGTCGGATTCCGTCAGGTCACTGATTTCCACTTGGTCAATCTGGCTGCCTGCCA
CTCTGCTCGCCTGGTCACCTTCGATCGGAAGCTTGCCCCGACCCTCGCACCTGAGGACCGTCGGTTCGTCCACAGTCTTT
AG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 7745.72 Da        Isoelectric Point: 4.3271

>AT25359 WP_041790612.1 NC_015635:c5518649-5518419 [Microlunatus phosphovorus NM-1]
MRTTLDLDPRVLTAARSRVNAGQNRSIGEAVSALALTGLATSSSSATTEANGLVLLPAAPGHVITDEMVAEALLDD

Download         Length: 231 bp

>AT25359 NC_015635:c5518649-5518419 [Microlunatus phosphovorus NM-1]
ATGAGAACGACCCTCGACTTGGACCCGCGAGTCCTCACTGCGGCACGCTCCCGGGTGAACGCAGGCCAGAACAGGAGTAT
CGGCGAGGCTGTCTCTGCCTTGGCGCTGACTGGCCTGGCCACATCGAGCTCCTCGGCGACTACCGAGGCCAACGGACTGG
TTCTGCTTCCGGCAGCTCCGGGGCACGTCATCACCGACGAGATGGTTGCCGAGGCACTCCTTGACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References